Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Department of Urology, The Fourth Affiliated Hospital of Anhui Medical University, Hefei 230012, China.
Int J Clin Pract. 2022 Aug 11;2022:4792451. doi: 10.1155/2022/4792451. eCollection 2022.
Prostate enlargement (PE) is an increase in prostate volume in morphology. PE was also observed in some patients aged <40 with chronic prostatitis. This study aimed to explore the associated factors for PE in Chinese adult men aged <40.
The medical records of 1851 consecutive Chinese adult men aged <40 in a single center were retrospectively analyzed. The checkup indicator characteristics between the PE and non-PE groups were compared by univariate analysis, and the associated factors were analyzed by multivariate analysis.
The overall prevalence of PE (defined as prostate volume ≥ 20 ml) in adult men aged < 40 was 10.4%. Age and the proportions of subjects with prostate calcification or hypertension were different between the PE and non-PE groups ( < 0.05). Multivariate logistic analysis showed that prostate calcification (odds ratio [OR], 1.831; 95% confidence interval [CI], 1.281-2.619; =0.001), hypertension (OR, 1.528; 95% CI, 1.125-2.076; =0.007), and age (OR, 1.117; 95% CI, 1.078-1.159; < 0.001) were associated factors for PE in adult men aged <40.
The prevalence of PE in Chinese adult check-up men aged <40 was not rare. In addition to age, prostate calcification and hypertension were associated factors for PE in Chinese adult men aged <40.
前列腺增大（PE）是指前列腺体积在形态上的增大。一些年龄<40 岁的慢性前列腺炎患者也观察到了这种情况。本研究旨在探讨中国<40 岁成年男性前列腺增大的相关因素。
回顾性分析了单中心 1851 例连续就诊的中国<40 岁成年男性的病历资料。采用单因素分析比较前列腺增大组和非前列腺增大组的体检指标特征，采用多因素分析探讨前列腺增大的相关因素。
<40 岁成年男性前列腺增大（定义为前列腺体积≥20ml）的总患病率为 10.4%。前列腺增大组和非前列腺增大组的年龄和前列腺钙化或高血压的比例不同（<0.05）。多因素 logistic 分析显示，前列腺钙化（比值比 [OR]，1.831；95%置信区间 [CI]，1.281-2.619；=0.001）、高血压（OR，1.528；95% CI，1.125-2.076；=0.007）和年龄（OR，1.117；95% CI，1.078-1.159；<0.001）是<40 岁成年男性前列腺增大的相关因素。
中国<40 岁成年男性体检人群中前列腺增大的患病率并不罕见。除了年龄，前列腺钙化和高血压也是中国<40 岁成年男性前列腺增大的相关因素。
