来自酿酒酵母的脱嘌呤内切核酸酶。
Apurinic endonucleases from Saccharomyces cerevisiae.
作者信息
Armel P R, Wallace S S
出版信息
Nucleic Acids Res. 1978 Sep;5(9):3347-56. doi: 10.1093/nar/5.9.3347.
Abstract
Three endonuclease activities have been partially purified from Saccharomyces cerevisiae on the basis of their activity against x-irradiated closed-circular supercoiled bacteriophage PM2 DNA. These endonucleases also nick apurinic DNA and two out of the three activities incise DNA UV-irradiated with high doses. The endonuclease activities have also been distinguished on the basis of their magnesium requirement and sensitivity to EDTA.
摘要
根据它们对经X射线照射的闭环超螺旋噬菌体PM2 DNA的活性，从酿酒酵母中部分纯化出了三种核酸内切酶活性。这些核酸内切酶也能切割脱嘌呤DNA，并且三种活性中的两种能切割高剂量紫外线照射的DNA。这些核酸内切酶活性还根据它们对镁的需求以及对EDTA的敏感性而得以区分。
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本文引用的文献
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The excision of pyrimidine dimers from DNA of ultraviolet irradiated yeast.从紫外线照射的酵母DNA中切除嘧啶二聚体。
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