Hosseininasab Dorsa, Shiraseb Farideh, Noori Sahar, Jamili Shahin, Mazaheri-Eftekhar Fatemeh, Dehghan Mahshid, da Silva Alessandra, Bressan Josefina, Mirzaei Khadijeh
Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Front Nutr. 2022 Aug 9;9:945591. doi: 10.3389/fnut.2022.945591. eCollection 2022.
Cardiovascular diseases (CVDs) are the leading cause of death globally. Based on recent studies, one of the factors that can have detrimental effects on CVD is the consumption of ultra-processed foods (UPFs). The current study investigated the relationship between UPF intake and cardiometabolic risk factors among Iranian women.
The current cross-sectional study was conducted on 391 women aged 18-65 years with a body mass index (BMI) ≥ 25 kg/m. Dietary intake was assessed using a 147-item food frequency questionnaire (FFQ). Anthropometric and biochemistry parameters were also collected. UPFs were identified using the NOVA classification.
In the present study, women had a mean (standard deviation) age of 36.67 (9.10) years and the mean BMI of 31.26 (4.29) kg/m. According to our findings, there was a significant association between UPF consumption and transforming growth factor (TGF) (β: 0.101, 95% CI: 0.023, 0.180, = 0.012), atherogenic coefficient (AC) (β: 0.011, 95% CI: 0.001, 0.032, = 0.034), visceral fat level (VFL) (β: 0.006, 95% CI: -0.017, 0.029, = 0.076), and the quantitative insulin sensitivity check index (QUICKI) (β: -3.775, 95%CI: 0.001, 0.001, = 0.042).
In conclusion, an increase in consumption of one gram of UPFs is associated with an increase in TGF, AC, and VFL but with a decrease in QUICKI. Despite this, further experimental studies are necessary to draw a more definite conclusion and disentangle the mechanisms by which UPFs may affect health.
心血管疾病（CVDs）是全球主要的死亡原因。根据最近的研究，超加工食品（UPFs）的消费是对心血管疾病可能产生有害影响的因素之一。本研究调查了伊朗女性中UPF摄入量与心脏代谢危险因素之间的关系。
本横断面研究针对391名年龄在18 - 65岁、体重指数（BMI）≥25 kg/m²的女性进行。使用147项食物频率问卷（FFQ）评估饮食摄入量。还收集了人体测量和生化参数。使用NOVA分类法识别UPFs。
在本研究中，女性的平均（标准差）年龄为36.67（9.10）岁，平均BMI为31.26（4.29）kg/m²。根据我们的研究结果，UPF消费与转化生长因子（TGF）（β：0.101，95%CI：0.023，0.180，P = 0.012）、致动脉粥样硬化系数（AC）（β：0.011，95%CI：0.001，0.032，P = 0.034）、内脏脂肪水平（VFL）（β：0.006，95%CI： - 0.017，0.029，P = 0.076）和定量胰岛素敏感性检查指数（QUICKI）（β： - 3.775，95%CI： - 0.001， - 0.001，P = 0.042）之间存在显著关联。
总之，每增加一克UPF的消费量与TGF、AC和VFL的增加相关，但与QUICKI的降低相关。尽管如此，仍需要进一步的实验研究来得出更明确的结论，并弄清楚UPFs可能影响健康的机制。
