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改性三氧化矿物凝聚体——一种多功能牙科材料:应用与最新进展洞察

Modified Mineral Trioxide Aggregate-A Versatile Dental Material: An Insight on Applications and Newer Advancements.

作者信息

Pushpalatha C, Dhareshwar Vismaya, Sowmya S V, Augustine Dominic, Vinothkumar Thilla Sekar, Renugalakshmi Apathsakayan, Shaiban Amal, Kakti Ateet, Bhandi Shilpa H, Dubey Alok, Rai Amulya V, Patil Shankargouda

机构信息

Department of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India.

Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India.

出版信息

Front Bioeng Biotechnol. 2022 Aug 9;10:941826. doi: 10.3389/fbioe.2022.941826. eCollection 2022.

Abstract

Mineral Trioxide Aggregate (MTA) has been a material of revolution in the field of dentistry since its introduction in the 1990s. It is being extensively used for perforation repairs, apexification, root-end filling, obturation, tooth fracture repair, regenerative procedures, apexogenesis, pulpotomies, and as a pulp-capping material because of its desired features such as biocompatibility, bioactivity, hydrophilicity, sealing ability, and low solubility. Even though its application is wide, it has its own drawbacks that prevent it from reaching its full potential as a comprehensive replacement material, including a long setting time, discoloration, mud-like consistency, and poor handling characteristics. MTA is a material of research interest currently, and many ongoing studies are still in process. In this review, the newer advancements of this versatile material by modification of its physical, chemical, and biological properties, such as change in its setting time, addressing the discoloration issue, inclusion of antimicrobial property, improved strength, regenerative ability, and biocompatibility will be discussed. Hence, it is important to have knowledge of the traditional and newer advancements of MTA to fulfill the shortcomings associated with the material.

摘要

自20世纪90年代引入以来,三氧化矿物凝聚体(MTA)一直是牙科领域的一项革命性材料。由于其具有生物相容性、生物活性、亲水性、密封能力和低溶解性等理想特性,它被广泛用于穿孔修复、根尖诱导成形术、根尖倒充填、根管充填、牙齿骨折修复、再生手术、牙根形成、牙髓切断术以及作为盖髓材料。尽管其应用广泛,但它也有自身的缺点,这些缺点阻碍了它作为一种全面替代材料发挥其全部潜力,包括凝固时间长、变色、泥状稠度和操作性能差。MTA是目前研究的热点材料,许多正在进行的研究仍在进行中。在这篇综述中,将讨论通过改变其物理、化学和生物学特性(如凝固时间的改变、解决变色问题、加入抗菌性能、提高强度、再生能力和生物相容性)对这种多功能材料进行的更新进展。因此,了解MTA的传统和更新进展对于弥补该材料相关的缺点很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44bb/9395930/6df1d730ad1a/fbioe-10-941826-g001.jpg

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