Department of Endodontology, Tsurumi University School of Dental Medicine.
Department of Operative Dentistry, Nihon University School of Dentistry.
Dent Mater J. 2019 Oct 2;38(5):693-700. doi: 10.4012/dmj.2018-193. Epub 2019 Jun 13.
The aim of this literature review was to assess the clinical performance of MTA to establish the evidence level for its effectiveness in vital pulp therapy, perforation repair, and retrograde root canal filling. A comprehensive literature survey was performed via electronic databases of PubMed/MEDLINE. A total of 58 papers were reviewed in this study, of which 2 were systematic reviews/meta-analysis, 9 were randomized controlled trials (RCTs), and the rest were fallen into other categories. Mineral trioxide aggregate (MTA) provided better pulp protection as a direct capping material when compared with calcium hydroxide. As perforation repair materials, MTA demonstrated an excellent sealing ability in vitro. For periodontal tissues around a perforation, MTA provided normal healing processes in clinical trials. It is therefore concluded that MTA has a high potential in repairing perforations. MTA is the most promising material when used for retrograde root canal filling demonstrating normal healing in short/long term clinical outcomes.
本文献综述旨在评估 MTA 的临床性能，以确定其在活髓治疗、穿孔修复和逆行根管充填方面有效性的证据水平。通过 PubMed/MEDLINE 电子数据库进行了全面的文献调查。本研究共回顾了 58 篇论文，其中 2 篇为系统评价/荟萃分析，9 篇为随机对照试验（RCT），其余则归入其他类别。与氢氧化钙相比，作为直接盖髓材料，矿物三氧化物聚合体（MTA）能更好地保护牙髓。作为穿孔修复材料，MTA 在体外具有优异的密封能力。对于穿孔周围的牙周组织，MTA 在临床试验中提供了正常的愈合过程。因此，MTA 具有修复穿孔的高潜力。MTA 是最有前途的逆行根管充填材料，在短期/长期临床结果中均显示出正常的愈合。
