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低剂量胸部 CT 用于 SARS-CoV-2 感染术前筛查。

Low-dose chest CT for preoperative screening for SARS-CoV-2 infection.

机构信息

Sección de imagen cardiotorácica, Servicio de Radiología, Clínica Universidad de Navarra, Pamplona, Navarra, Spain.

Sección de imagen cardiotorácica, Servicio de Radiología, Clínica Universidad de Navarra, Pamplona, Navarra, Spain.

出版信息

Radiologia (Engl Ed). 2022 Jul-Aug;64(4):317-323. doi: 10.1016/j.rxeng.2021.11.004. Epub 2022 Jul 21.

Abstract

INTRODUCTION

This study aimed to evaluate the role of chest computed tomography (CT) in complementing reverse transcription polymerase chain reaction (RT-PCR) in asymptomatic candidates for elective surgery in the context of the COVID-19 pandemic.

MATERIAL AND METHODS

We prospectively included 464 asymptomatic patients who underwent a triple screening workup for SARS-CoV-2 infection (health questionnaire, RT-PCR, and low-dose chest CT) during the 48 h prior to undergoing elective surgery. A positive RT-PCR and/or CT findings suggestive of COVID-19 (CO-RADS 4/5) were considered diagnostic criteria for SARS-CoV-2 infection.

RESULTS

Most patients (64.7%) underwent otorhinolaryngology surgery. No patients had positive RT-PCR results or symptoms suggestive of SARS-CoV-2 in the health questionnaire. Only 22 (4.7%) had signs compatible with lung infection; in 20 of these, the CT findings were atypical or indeterminate for COVID-19 (CO-RADS 2/3) and in 2 they were compatible with COVID-19 pneumonia in resolution. In the immediate postoperative period, no cases of SARS-CoV-2 infection were confirmed.

CONCLUSION

In our series of asymptomatic patients, low-dose CT did not add any value to the results of RT-PCR and a health questionnaire in preoperative screening for SARS-CoV-2.

摘要

简介

本研究旨在评估胸部计算机断层扫描(CT)在补充逆转录聚合酶链反应(RT-PCR)方面的作用,以在 COVID-19 大流行背景下对择期手术的无症状候选者进行检测。

材料与方法

我们前瞻性纳入了 464 名无症状患者,这些患者在择期手术前 48 小时内接受了 SARS-CoV-2 感染的三重筛查(健康问卷、RT-PCR 和低剂量胸部 CT)。阳性 RT-PCR 和/或提示 COVID-19 的 CT 表现(CO-RADS 4/5)被视为 SARS-CoV-2 感染的诊断标准。

结果

大多数患者(64.7%)接受耳鼻喉科手术。没有患者的 RT-PCR 结果或健康问卷出现 SARS-CoV-2 症状。只有 22 名(4.7%)有肺部感染的迹象;在这 20 名患者中,CT 表现为非典型或不确定的 COVID-19(CO-RADS 2/3),在 2 名患者中,CT 表现与 COVID-19 肺炎的恢复一致。在术后即刻,未确认有 SARS-CoV-2 感染病例。

结论

在我们的无症状患者系列中,低剂量 CT 并未在 SARS-CoV-2 的术前筛查中为 RT-PCR 和健康问卷的结果提供任何额外价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3517/9300583/238e1f28e7a0/gr1_lrg.jpg

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