Kim Na Yeon, Yoo Seo-Koo, Jin Jae-Chan, Yoon Youn Jung, Han Doug Hyun, Kim Sun Mi
Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
School of Social Welfare, Soongsil University, Seoul, Republic of Korea.
J Acad Consult Liaison Psychiatry. 2023 Mar-Apr;64(2):136-146. doi: 10.1016/j.jaclp.2022.08.005. Epub 2022 Aug 27.
Over 80% of perimenopausal women experience various physical and neuropsychiatric symptoms due to changes in hormones. However, accurate evaluation and treatment of menopausal symptoms are lacking due to limited evidence regarding customized treatment for each symptom type.
This study aimed to identify and cluster psychosomatic symptoms in Korean perimenopausal women and to investigate the characteristics of each cluster type.
This Web-based survey assessed 1060 Korean perimenopausal women recruited from nationally representative panels available from a commercial research company. Menopausal symptoms were evaluated using the Menopause Rating Scale, Patient Health Questionnaire-15, Patient Health Questionnaire-9, Insomnia Severity Index, Subjective Memory Complaints Questionnaire, and Overactive Bladder Symptom Score. Data were analyzed using latent profile analysis and multinomial logistic regression.
Latent profile analysis identified 4 latent classes: "all unimpaired (class 1)," "impaired sexual function, while others are unimpaired (class 2)," "unimpaired sexual function, while others are impaired (class 3)," and "all impaired (class 4)." Classes 3 and 4 were significantly more likely to have a family history of perimenopausal syndrome and a history of other mental disorders, postpartum depression, and postpartum psychosis than classes 1 and 2.
Psychosomatic symptoms appear during perimenopause along with depression, somatic symptoms, insomnia, impaired memory, and overactive bladder symptoms. Individuals with these symptoms are more likely to have a history of postpartum depression, psychosis, and other psychiatric disorders. Therefore, sexual dysfunction must be independently treated. Further studies are needed to develop and verify individualized treatments according to symptom class.
超过80%的围绝经期女性因激素变化而出现各种身体和神经精神症状。然而，由于针对每种症状类型的定制治疗证据有限，对更年期症状的准确评估和治疗尚显不足。
本研究旨在识别和聚类韩国围绝经期女性的心身症状，并调查每种聚类类型的特征。
这项基于网络的调查评估了从一家商业研究公司提供的全国代表性样本中招募的1060名韩国围绝经期女性。使用更年期评定量表、患者健康问卷-15、患者健康问卷-9、失眠严重程度指数、主观记忆障碍问卷和膀胱过度活动症状评分来评估更年期症状。数据采用潜在剖面分析和多项逻辑回归进行分析。
潜在剖面分析确定了4个潜在类别：“全部未受损（类别1）”、“性功能受损，其他未受损（类别2）”、“性功能未受损，其他受损（类别3）”和“全部受损（类别4）”。与类别1和2相比，类别3和4有围绝经期综合征家族史以及其他精神障碍、产后抑郁症和产后精神病病史的可能性显著更高。
心身症状在围绝经期出现，同时伴有抑郁、躯体症状、失眠、记忆障碍和膀胱过度活动症状。有这些症状的个体更有可能有产后抑郁症、精神病和其他精神障碍病史。因此，性功能障碍必须单独治疗。需要进一步研究来开发和验证根据症状类别进行的个体化治疗。
