一名90岁患者在甲状腺切除和放疗12年后出现甲状腺滤泡癌乳腺转移。
Breast metastasis from thyroid follicular carcinoma in a 90-year-old patient 12 years after thyroidectomy and radiotherapy.
作者信息
Taha Ahmed, Khalil Abdalla, Khan Mihir, Metafa Anna
机构信息
Medical Imaging Department, Princess Royal University Hospital, London, UK.
Acute Medicine Department, Northwick Park Hospital, London North West University Healthcare, northwick park hospital, London, HA13UJ, UK.
出版信息
Radiol Case Rep. 2022 Aug 12;17(10):3911-3914. doi: 10.1016/j.radcr.2022.07.047. eCollection 2022 Oct.
INTRODUCTION
Secondary lesions in the breast from extramammary malignancies are rarely encountered in medical practice. Medical imaging of the breast (mammography and ultrasonography) may not differentiate between a primary breast mass and a secondary tumor from an extramammary malignancy.
CASE DESCRIPTION
A 90-year-old woman with a history of thyroid cancer, skin metastasis, thyroidectomy, and radiotherapy 12 years prior presented with pain in the left breast and no palpable masses in either breast or axilla. Mammography and ultrasonography of the breast confirmed a suspicious lesion in the upper outer quadrant of the left breast. Histopathology of the core biopsy, including immune histochemistry staining of the lesion, confirmed secondary follicular carcinoma of the thyroid.
CONCLUSION
Thyroid cancer is a rare extramammary malignancy that may metastasize to the breast; however, it may rarely occur a few years after thyroidectomy and radiotherapy.
引言
乳腺外恶性肿瘤所致的乳腺继发性病变在医疗实践中很少见。乳腺的医学成像（乳腺X线摄影和超声检查）可能无法区分原发性乳腺肿块和乳腺外恶性肿瘤的继发性肿瘤。
病例描述
一名90岁女性，有甲状腺癌病史、皮肤转移、甲状腺切除术史，12年前接受过放疗，现出现左乳疼痛，双侧乳房及腋窝均未触及肿块。乳腺X线摄影和超声检查证实左乳外上象限有一个可疑病变。粗针活检的组织病理学检查，包括病变的免疫组织化学染色，证实为甲状腺继发性滤泡癌。
结论
甲状腺癌是一种罕见的乳腺外恶性肿瘤，可转移至乳腺；然而，它很少在甲状腺切除术后和放疗后数年发生。
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