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塞拉利昂的盘尾丝虫病。一、关于格拜马村患病率和传播情况的研究。

Onchocerciasis in Sierra Leone. I. Studies on the prevalence and transmission at Gbaiima village.

作者信息

McMahon J E, Davies J B, White M D, Goddard J M, Beech-Garwood P A, Kirkwood B R

出版信息

Trans R Soc Trop Med Hyg. 1986;80(5):802-9. doi: 10.1016/0035-9203(86)90389-5.

DOI:10.1016/0035-9203(86)90389-5
PMID:3603620
Abstract

A longitudinal survey--parasitological, clinical, immunological and entomological--of onchocerciasis is being conducted in Gbaiima village in Sierra Leone. The estimated Annual Transmission Potential (ATP) is 5863. More than 80% of the annual transmission occurs between October and December. Four species of the Simulium damnosum complex are known to breed in a nearby river. The relative role of these species as vectors has yet to be determined. The total population (598 persons) aged one year and over were examined. Based on microfilarial and nodular rates the prevalence of onchocerciasis was 68.6%. In persons above 15 years of age this prevalence was 88.9%. Microfilarial and nodular rates were related to age. Severe skin lesions occurred in 1.0% of persons. 24 adults (7.5%) were blind (but the cause of the blindness was not determined).

摘要

在塞拉利昂的盖伊马村正在开展一项关于盘尾丝虫病的纵向调查,涵盖寄生虫学、临床、免疫学和昆虫学方面。估计的年传播潜能(ATP)为5863。超过80%的年度传播发生在10月至12月之间。已知有四种恶蚋复合体在附近一条河流中繁殖。这些物种作为传播媒介的相对作用尚待确定。对一岁及以上的总人口(598人)进行了检查。根据微丝蚴率和结节率,盘尾丝虫病的患病率为68.6%。15岁以上人群的患病率为88.9%。微丝蚴率和结节率与年龄有关。1.0%的人出现严重皮肤病变。24名成年人(7.5%)失明(但失明原因未确定)。

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引用本文的文献

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Visual loss in an onchocerciasis endemic community in Sierra Leone.在塞拉利昂一个盘尾丝虫病流行社区中的视力丧失情况。
Br J Ophthalmol. 1993 Jan;77(1):30-2. doi: 10.1136/bjo.77.1.30.
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A histocytochemical study of the macrophages present in tissue responses to adult Onchocerca volvulus.对成年盘尾丝虫组织反应中存在的巨噬细胞的组织化学研究。
Histochem J. 1987 Sep;19(9):509-19. doi: 10.1007/BF01675422.
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Community-based treatment of onchocerciasis with ivermectin: acceptability and early adverse reactions.基于社区用伊维菌素治疗盘尾丝虫病:可接受性和早期不良反应。
Bull World Health Organ. 1989;67(6):721-30.
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Suppression of human lymphocyte responses to specific and non-specific stimuli in human onchocerciasis.人类盘尾丝虫病患者中人类淋巴细胞对特异性和非特异性刺激反应的抑制
Clin Exp Immunol. 1991 Dec;86(3):433-9. doi: 10.1111/j.1365-2249.1991.tb02949.x.