Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Piazzale Gambuli, 1, 06132, Perugia, Italy.
Innovation Lab, Integris S.P.A, Rende and Pisa, Italy.
Aging Clin Exp Res. 2022 Nov;34(11):2721-2731. doi: 10.1007/s40520-022-02219-4. Epub 2022 Aug 29.
Based on recent researches on the use of natural language processing techniques for very early detection of cognitive decline and the benefits of cognitive stimulation for people with cognitive impairments, the Dementia Monitoring application (DMapp) is developed inside the Memento project.
The aims of this work are: (1) to present DMapp; (2) to report the results of two preliminary studies on DMapp; (3) to describe the clinical and experimental potentiality of DMapp.
Italian people with the diagnosis of mild cognitive impairment due to Alzheimer's disease or dementia due to Alzheimer's Disease with a Mini-Mental-State-Examination between 24 and 28 (inclusive) were involved in the DMapp development prototype during the Lab Trial (4 subjects) and Filed Trial (5 subjects) of the Memento project. Qualitative and quantitative data were collected to evaluate participants' opinions, the DMapp ability to perform the automatic analysis of the speech and participants' visible emotional state effective. Ad hoc interviews, the Observed Emotion Rating Scale and performance metrics to solve different tasks were used. The relation between cognitive measures (global cognitive measures) and linguistic indexes values was considered using Euclidean distances between the participants.
Linguistic indexes were calculated and seemed to classify the participants' performance as expected from cognitive measures. The DMapp was appreciated by people with cognitive impairment. Positive emotions were present.
DMapp seems an interesting approach to monitor dementia symptoms progression and stimulate memory. Possible developments and open questions are discussed.
基于最近对自然语言处理技术在认知能力下降早期检测中的应用以及认知刺激对认知障碍者的益处的研究，Memento 项目内部开发了痴呆监测应用程序（DMapp）。
本工作的目的是：（1）介绍 DMapp；（2）报告 DMapp 的两项初步研究结果；（3）描述 DMapp 的临床和实验潜力。
在 Memento 项目的实验室试验（4 名受试者）和现场试验（5 名受试者）中，患有轻度认知障碍（阿尔茨海默病引起）或因阿尔茨海默病导致痴呆（Mini-Mental-State-Examination 评分为 24-28 分）的意大利人参与了 DMapp 开发原型。收集定性和定量数据以评估参与者的意见、DMapp 自动分析语音的能力以及参与者的可见情绪状态的有效性。使用专门的访谈、观察情绪评分量表和解决不同任务的性能指标。考虑到参与者之间的欧几里得距离，将认知测量（总体认知测量）和语言指标值之间的关系。
计算了语言指标，似乎根据认知测量结果对参与者的表现进行了分类。认知障碍者对 DMapp 表示赞赏。出现了积极的情绪。
DMapp 似乎是监测痴呆症状进展和刺激记忆的一种有趣方法。讨论了可能的发展和开放问题。
