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近年来在生物医学、临床和环境应用领域设计纤维生物材料方面的进展。

Recent Advances in Designing Fibrous Biomaterials for the Domain of Biomedical, Clinical, and Environmental Applications.

机构信息

Department of Chemistry and Nanotechnology, The School of Engineering and Science, Tecnologico de Monterrey, Monterrey, Nuevo Leon 64849, Mexico.

Department of Chemical Engineering, The School of Engineering and Science, Tecnologico de Monterrey, Monterrey, Nuevo Leon 64988, Mexico.

出版信息

ACS Biomater Sci Eng. 2022 Sep 12;8(9):3690-3716. doi: 10.1021/acsbiomaterials.2c00786. Epub 2022 Aug 29.

Abstract

Unique properties and potential applications of nanofibers have emerged as innovative approaches and opportunities in the biomedical, healthcare, environmental, and biosensor fields. Electrospinning and centrifugal spinning strategies have gained considerable attention among all kinds of strategies to produce nanofibers. These techniques produce nanofibers with high porosity and surface area, adequate pore architecture, and diverse chemical compositions. The extraordinary characteristics of nanofibers have unveiled new gates in nanomedicine to establish innovative fiber-based formulations for biomedical use, healthcare, and a wide range of other applications. The present review aims to provide a comprehensive overview of nanofibers and their broad range of applications, including drug delivery, biomedical scaffolds, tissue/bone-tissue engineering, dental applications, and environmental remediation in a single place. The review begins with a brief introduction followed by potential applications of nanofibers. Finally, the future perspectives and current challenges of nanofibers are demonstrated. This review will help researchers to engineer more efficient multifunctional nanofibers with improved characteristics for their effective use in broad areas. We strongly believe this review is a reader's delight and will help in dealing with the fundamental principles and applications of nanofiber-based scaffolds. This review will assist students and a broad range of scientific communities to understand the significance of nanofibers in several domains of nanotechnology, nanomedicine, biotechnology, and environmental remediation, which will set a benchmark for further research.

摘要

纳米纤维具有独特的性质和潜在的应用,成为生物医学、医疗保健、环境和生物传感器领域的创新方法和机会。在所有生产纳米纤维的策略中,静电纺丝和离心纺丝策略受到了极大的关注。这些技术生产的纳米纤维具有高孔隙率和比表面积、适当的孔结构和多样化的化学成分。纳米纤维的非凡特性为纳米医学开辟了新的途径,为生物医学用途、医疗保健以及广泛的其他应用建立了创新的纤维基配方。本综述旨在提供纳米纤维及其广泛应用的综合概述,包括药物输送、生物医学支架、组织/骨组织工程、牙科应用和环境修复。综述从简介开始,然后介绍纳米纤维的潜在应用。最后,展示了纳米纤维的未来展望和当前挑战。本综述将帮助研究人员设计更高效的多功能纳米纤维,以改善其在广泛领域的有效应用。我们坚信,本综述将受到读者的欢迎,并有助于理解基于纳米纤维支架的基本原理和应用。本综述将帮助学生和广泛的科学界理解纳米纤维在纳米技术、纳米医学、生物技术和环境修复等多个领域的重要性,为进一步的研究奠定基础。

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