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使用多模态身体活动传感数据进行多任务深度学习,以实现对患者住院时间和再入院状态的经济高效预测。

Multitask Deep Learning for Cost-Effective Prediction of Patient's Length of Stay and Readmission State Using Multimodal Physical Activity Sensory Data.

作者信息

Ali Sajid, El-Sappagh Shaker, Ali Farman, Imran Muhammad, Abuhmed Tamer

出版信息

IEEE J Biomed Health Inform. 2022 Dec;26(12):5793-5804. doi: 10.1109/JBHI.2022.3202178. Epub 2022 Dec 7.

Abstract

In a hospital, accurate and rapid mortality prediction of Length of Stay (LOS) is essential since it is one of the essential measures in treating patients with severe diseases. When predictions of patient mortality and readmission are combined, these models gain a new level of significance. Therefore, the most expensive components of patient care are LOS and readmission rates. Several studies have assessed readmission to the hospital as a single-task issue. The performance, robustness, and stability of the model increase when many correlated tasks are optimized. This study develops multimodal multitasking Long Short-Term Memory (LSTM) Deep Learning (DL) model that can predict both LOS and readmission for patients using multi-sensory data from 47 patients. Continuous sensory data is divided into eight sections, each of which is recorded for an hour. The time steps are constructed using a dual 10-second window-based technique, resulting in six steps per hour. The 30 statistical features are computed by transforming the sensory input into the resulting vector. The proposed multitasking model predicts 30-day readmission as a binary classification problem and LOS as a regression task by constructing discrete time-step data based on the length of physical activity during a hospital stay. The proposed model is compared to a random forest for a single-task problem (classification or regression) because typical machine learning algorithms are unable to handle the multitasking challenge. In addition, sensory data combined with other cost-effective modalities such as demographics, laboratory tests, and comorbidities to construct reliable models for personalized, cost-effective, and medically acceptable prediction. With a high accuracy of 94.84%, the proposed multitask multimodal DL model classifies the patient's readmission status and determines the patient's LOS in hospital with a minimal Mean Square Error (MSE) of 0.025 and Root Mean Square Error (RMSE) of 0.077, which is promising, effective, and trustworthy.

摘要

在医院中,准确且快速地预测住院时长(LOS)的死亡率至关重要,因为这是治疗重症患者的关键指标之一。当将患者死亡率和再入院率的预测结合起来时,这些模型就具有了新的重要意义。因此,患者护理中最昂贵的部分是住院时长和再入院率。多项研究已将医院再入院评估为一个单任务问题。当优化许多相关任务时,模型的性能、稳健性和稳定性会提高。本研究开发了一种多模态多任务长短期记忆(LSTM)深度学习(DL)模型,该模型可以使用来自47名患者的多感官数据预测患者的住院时长和再入院情况。连续的感官数据被分为八个部分,每个部分记录一小时。时间步长采用基于10秒双窗口的技术构建,每小时产生六个步长。通过将感官输入转换为结果向量来计算30个统计特征。所提出的多任务模型通过基于住院期间身体活动时长构建离散时间步长数据,将30天再入院预测为二元分类问题,将住院时长预测为回归任务。由于典型的机器学习算法无法应对多任务挑战,因此将所提出的模型与用于单任务问题(分类或回归)的随机森林进行比较。此外,将感官数据与其他具有成本效益的模式(如人口统计学、实验室检查和合并症)相结合,以构建可靠的模型,用于个性化、具有成本效益且医学上可接受的预测。所提出的多任务多模态DL模型以94.84%的高精度对患者的再入院状态进行分类,并以最小均方误差(MSE)0.025和均方根误差(RMSE)0.077确定患者的住院时长,这是有前景的、有效的且值得信赖的。

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