Key Laboratory of Public Health Safety of Hebei Province, School of Public Health, Hebei University, Baoding, China.
Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, National Institutes for Food and Drug Control, Beijing, China.
J Med Virol. 2023 Jan;95(1):e28103. doi: 10.1002/jmv.28103. Epub 2022 Sep 7.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing the ongoing global coronavirus disease 2019 (COVID-19) pandemic, is believed to be transmitted primarily through respiratory droplets and aerosols. However, reports are increasing regarding the contamination of environmental surfaces, shared objects, and cold-chain foods with SARS-CoV-2 RNA and the possibility of environmental fomite transmission of the virus raises much concern and debate. This study summarizes the current knowledge regarding potential mechanisms of environmental transmission of SARS-CoV-2, including the prevalence of surface contamination in various settings, the viability and stability of the virus on surfaces or fomites, as well as environmental factors affecting virus viability and survival such as temperature and relative humidity. Instances of fomite transmission, including cold-chain food transmission, and the importance of fomite transmission in epidemics, are discussed. The knowledge gaps regarding fomite transmission of SARS-CoV-2 are also briefly analyzed.
严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)是导致当前全球 2019 年冠状病毒病(COVID-19)大流行的病毒,据信主要通过呼吸道飞沫和气溶胶传播。然而,关于环境表面、共享物品和冷链食品被 SARS-CoV-2 RNA 污染的报告越来越多,病毒通过环境污染物传播的可能性引起了极大的关注和争议。本研究总结了关于 SARS-CoV-2 环境传播潜在机制的现有知识,包括各种环境中表面污染的普遍性、病毒在表面或污染物上的存活和稳定性,以及影响病毒存活和生存的环境因素,如温度和相对湿度。讨论了包括冷链食品传播在内的接触传播实例,以及接触传播在传染病中的重要性。还简要分析了 SARS-CoV-2 接触传播的知识空白。