Department of Social & Preventive Medicine, Centre for Epidemiology & Evidence-Based Practice, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
School of Medicine, International Medical University, Kuala Lumpur, Malaysia.
PLoS One. 2022 Aug 30;17(8):e0273364. doi: 10.1371/journal.pone.0273364. eCollection 2022.
Patients with COVID-19 usually recover and return to normal health, however some patients may have symptoms that last for weeks or even months after recovery. This persistent state of ill health is known as Long COVID if it continues for more than three months and are not explained by an alternative diagnosis. Long Covid has been overlooked, especially in the low- and middle-income countries. Therefore, we conducted an online survey among the COVID-19 survivors in the community to explore their Long COVID symptoms, factors associated with Long COVID and how Long COVID affected their work. A total of 732 COVID-19 survivors responded, with 56% were without or with mild symptoms during their acute COVID-19 conditions. One in five COVID-19 survivors reported of experiencing Long COVID. The most commonly reported symptoms were fatigue, brain fog, depression, anxiety and insomnia. Females had 58% higher odds (95% CI: 1.02, 2.45) of experiencing Long COVID. Patients with moderate and severe levels of acute COVID-19 symptoms had OR of 3.01 (95% CI: 1.21, 7.47) and 3.62 (95% CI: 1.31, 10.03) respectively for Long COVID. Recognition of Long COVID and its associated factors is important in planning prevention, rehabilitation, clinical management to improve recovery from COVID-19.
患者感染 COVID-19 后通常会康复并恢复正常健康，但有些患者在康复后可能会出现持续数周甚至数月的症状。如果这种持续的健康不佳状态持续超过三个月，且无法用其他诊断来解释，则称为长新冠。长新冠在低收入和中等收入国家被忽视了。因此，我们在社区内对 COVID-19 幸存者进行了一项在线调查，以探讨他们的长新冠症状、与长新冠相关的因素以及长新冠如何影响他们的工作。共有 732 名 COVID-19 幸存者做出回应，其中 56%在急性 COVID-19 期间没有或只有轻微症状。五分之一的 COVID-19 幸存者报告有长新冠症状。最常见的报告症状是疲劳、脑雾、抑郁、焦虑和失眠。女性经历长新冠的可能性高出 58%（95%CI：1.02，2.45）。急性 COVID-19 症状中度和重度的患者经历长新冠的 OR 分别为 3.01（95%CI：1.21，7.47）和 3.62（95%CI：1.31，10.03）。认识长新冠及其相关因素对于规划预防、康复和临床管理以改善 COVID-19 康复非常重要。
