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单静脉通路血小板去除术:Haemonetics V-50与Fenwal CS-3000血细胞分离机的比较

Plateletapheresis using single vein access: a comparison of Haemonetics V-50 and Fenwal CS-3000 blood cell separators.

作者信息

Vados W, Thompson H, Scott E

出版信息

Vox Sang. 1987;52(3):195-9. doi: 10.1111/j.1423-0410.1987.tb03026.x.

DOI:10.1111/j.1423-0410.1987.tb03026.x
PMID:3604178
Abstract

Donors were randomly selected for plateletapheresis using either the Haemonetics V-50 surge procedure or the Fenwal CS-3000 with special modifications. Six procedures using the V-50 were performed with 6 collection cycles. Platelet yields averaged 3.9 X 10(11) with an average white cell contamination of 3.8 X 10(8). Ten procedures were performed with 8 collection cycles. Platelet yields averaged 4.5 X 10(11) with an average white cell contamination of 1.2 X 10(8). CS-3000 procedures were performed using either 4,000 or 4,800 ml whole blood processed as the endpoint. Concentrates obtained using 4,000 ml (n = 10) as the endpoint contained 3.9 X 10(11) platelets with a white cell contamination of 9.2 X 10(8). A 4,800 ml (n = 5) endpoint produced concentrates with a yield of 4.5 X 10(11) and white cell contamination of 10.4 X 10(8).

摘要

供体通过使用血细胞分离机V - 50的快速程序或经过特殊改良的芬瓦勒CS - 3000随机选择进行血小板单采。使用V - 50进行了6次程序,共6个采集周期。血小板产量平均为3.9×10¹¹,平均白细胞污染为3.8×10⁸。进行了10次程序,共8个采集周期。血小板产量平均为4.5×10¹¹,平均白细胞污染为1.2×10⁸。CS - 3000程序以处理4000毫升或4800毫升全血作为终点。以4000毫升(n = 10)作为终点获得的浓缩物含有3.9×10¹¹个血小板,白细胞污染为9.2×10⁸。以4800毫升(n = 5)作为终点产生的浓缩物产量为4.5×10¹¹,白细胞污染为10.4×10⁸。

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