Plateletapheresis using single vein access: a comparison of Haemonetics V-50 and Fenwal CS-3000 blood cell separators.

Donors were randomly selected for plateletapheresis using either the Haemonetics V-50 surge procedure or the Fenwal CS-3000 with special modifications. Six procedures using the V-50 were performed with 6 collection cycles. Platelet yields averaged 3.9 X 10(11) with an average white cell contamination of 3.8 X 10(8). Ten procedures were performed with 8 collection cycles. Platelet yields averaged 4.5 X 10(11) with an average white cell contamination of 1.2 X 10(8). CS-3000 procedures were performed using either 4,000 or 4,800 ml whole blood processed as the endpoint. Concentrates obtained using 4,000 ml (n = 10) as the endpoint contained 3.9 X 10(11) platelets with a white cell contamination of 9.2 X 10(8). A 4,800 ml (n = 5) endpoint produced concentrates with a yield of 4.5 X 10(11) and white cell contamination of 10.4 X 10(8).