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急性冠状动脉综合征患者的生活质量与抑郁评估:一项横断面研究。

Quality of Life and Depression Assessment in Patients with Acute Coronary Syndrome: A Cross-Sectional Study.

作者信息

Varghese Treesa P, Kumar P R Anand Vijaya

机构信息

Department of Pharmacy Practice, Yenepoya Pharmacy College and Research Centre (Yenepoya deemed to be University), Deralakatte, Mangalore, India.

Department of Pharmacology, JSS Academy of Higher Education and Research Centre (JSSAHER), JSS College of Pharmacy, Ooty, India.

出版信息

Cardiovasc Hematol Disord Drug Targets. 2022;22(3):155-161. doi: 10.2174/1871529X22666220830093651.

Abstract

PURPOSE

Acute Coronary Syndrome (ACS) is currently the leading cause of death in industrialized countries. Morbidity after ACS includes physical and mental disorders affecting the patient's whole life situation and Quality of Life (QoL). The main aim of the study was to assess QoL and depression among post-ACS patients.

METHODS

This was a cross-sectional observational study. A total of 112 patients who fulfilled the inclusion criteria were included in this study. A semi-structured questionnaire was administered to the patients to collect data from the patients. In this study, men and women aged 18 - 80 with ACS; patients diagnosed with Non-ST Segment Elevated Myocardial Infarction (NSTEMI) or STEMI or Angina Pectoris were included. Patients with severe mental, and physical illness and dementia were excluded from the study. QoL and depression assessment was done by RAND 36-Item Health Survey and Hamilton Depression Rating scale, respectively.

RESULTS

Among 112 post-ACS patients, 78 patients were males, and 38 patients were females. The mean age of the study population was 64.25 ± 9.029 and with most individuals in the category of 61 -70 years. The majority of study populations were married (71.5%) and lived with their families (92.9%). In this study group, 42.9 % of the population reported at least high school education (SSLC) and 54.5% were full-time employees. Most of the patients (91.1%) were taking the medication regularly, while 55.4% of patients reported regular compliance with the follow-up. This study identified that, among various factors, older age, female gender, lower income, unemployment, low education status, poor compliance with medication, and depressive symptoms led to poor QoL.

CONCLUSION

This study confirms a negative correlation between depressive symptoms and QoL. This study's results reveal the magnitude of depression that is prevalent in the primary health care clinic that goes undiagnosed and unmanaged. Hence, it is recommended to properly screen depressive symptoms in ACS patients. Therefore, concurrently, better QoL can be achieved by managing both depression and ACS.

摘要

目的

急性冠状动脉综合征(ACS)目前是工业化国家的主要死因。ACS后的发病率包括影响患者整个生活状况和生活质量(QoL)的身心障碍。本研究的主要目的是评估ACS后患者的生活质量和抑郁情况。

方法

这是一项横断面观察性研究。共有112名符合纳入标准的患者纳入本研究。向患者发放半结构化问卷以收集数据。本研究纳入年龄在18 - 80岁的患有ACS的男性和女性;诊断为非ST段抬高型心肌梗死(NSTEMI)、ST段抬高型心肌梗死(STEMI)或心绞痛的患者。患有严重精神和身体疾病以及痴呆症的患者被排除在研究之外。生活质量和抑郁评估分别通过兰德36项健康调查和汉密尔顿抑郁评定量表进行。

结果

在112名ACS后患者中,78名是男性,38名是女性。研究人群的平均年龄为64.25±9.029岁,大多数人年龄在61 - 70岁之间。大多数研究人群已婚(71.5%)并与家人同住(92.9%)。在该研究组中,42.9%的人群报告至少接受过高中教育(SSLC),54.5%是全职员工。大多数患者(91.1%)定期服药,而55.4%的患者报告定期遵守随访。本研究确定,在各种因素中,年龄较大、女性、收入较低、失业、教育程度低、服药依从性差和抑郁症状导致生活质量较差。

结论

本研究证实抑郁症状与生活质量之间存在负相关。本研究结果揭示了在初级卫生保健诊所中普遍存在但未被诊断和管理的抑郁程度。因此,建议对ACS患者进行抑郁症状的适当筛查。因此,同时通过管理抑郁和ACS可以实现更好的生活质量。

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