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Acta Biomed. 2022 Aug 31;93(4):e2022264. doi: 10.23750/abm.v93i4.12448.
Background Asthma control is the goal of the management, but some patients do not achieve adequate control. Adherence to prescriptions is a relevant factor in this issue. As very few studies addressed this problem in adolescents, we investigated this aspect in this setting. Methods This cross-sectional study consecutively enrolled 87 adolescents (60 males, 27 females, median age 14.2 years) with asthma visited at a third-level pediatric clinic. We used two questionnaires: Morisky Medication Adherence Scale (MMAS-8) and TAI. Results As regards MMAS-8, 23 (26.6%) adolescents had low adherence, 34 (39%) medium, and 30 (34.4%) high. Concerning TAI, 34 (39%) had low adherence, 43 (49.5%) medium, and 10 (11.5%) high. After stratification per asthma control grade, adolescents with partly-controlled asthma had the highest scores for medium adherence (p=0.0017 and 0.049, respectively for MMAS-8 and TAI). Conclusions Adolescents with asthma have poor adherence independently to the asthma control grade. This failure implicates that more attention should be paid to this issue in clinical practice.
哮喘控制是管理的目标，但有些患者无法达到足够的控制。遵医嘱是解决这个问题的一个相关因素。由于很少有研究在青少年中探讨这个问题，我们在这个背景下对此进行了调查。
本横断面研究连续纳入了 87 名在三级儿科诊所就诊的哮喘青少年（60 名男性，27 名女性，中位年龄 14.2 岁）。我们使用了两种问卷：Morisky 用药依从性量表（MMAS-8）和 TAI。
就 MMAS-8 而言，23 名（26.6%）青少年的依从性低，34 名（39%）为中，30 名（34.4%）为高。就 TAI 而言，34 名（39%）的依从性低，43 名（49.5%）为中，10 名（11.5%）为高。按哮喘控制程度分层后，部分控制哮喘的青少年在中依从性方面的评分最高（p=0.0017 和 0.049，分别用于 MMAS-8 和 TAI）。
哮喘青少年的依从性差，与哮喘控制程度无关。这一失败表明，在临床实践中应更加关注这一问题。
