Department of Biological Psychology, VU University, and Amsterdam Public Health research institute, VU University Medical Center, Amsterdam, The Netherlands.
Exerc Sport Sci Rev. 2023 Jan 1;51(1):2-18. doi: 10.1249/JES.0000000000000305. Epub 2022 Sep 1.
Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs.
双胞胎和家系研究表明，遗传因素对通过自我报告或加速度计评估的身体活动（PA）有很大贡献。PA 的遗传力在整个生命周期中约为 43%。全基因组关联研究表明，与运动能力和运动享受相关的生物学途径。基于影响 PA 的遗传变异的多基因评分可能有助于提高干预计划的成功率。
