Kasivalu Justus K, Omwenga George I, Aboge Gabriel O
Department of Biochemistry, Microbiology and Biotechnology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya.
Department of Public Health, Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Nairobi, Nairobi, Kenya.
Int J Microbiol. 2022 Aug 22;2022:9349303. doi: 10.1155/2022/9349303. eCollection 2022.
infection is common in Kenya though there is little knowledge of the genetic diversity of the pathogen. is part of the normal flora in the respiratory tract of camels, but it becomes pathogenic when the resistance of the camel body is diminished by bad ecological conditions. This study was conducted to detect, characterize, and determine the genetic diversity of infecting camels in Marsabit and Turkana Counties. The KMT1 gene was targeted as the marker gene for and , and as marker genes for capsular serogroups A, B, D, E, and F, respectively. Out of 102 blood and 30 nasal swab samples, twenty-one samples (16%) were confirmed to be positive for and only capsular group E was detected in both counties. The sequences were highly conserved and were related to strains from other parts of the world. Our study has confirmed that camels in Marsabit and Turkana Counties of Kenya are infected by of capsular type E. Farmers should not underfeed camels, ensure appropriate medication and vaccination programs, and minimize herding of camels in crowded areas especially in wet conditions in order to slow the spread of infection.
在肯尼亚,感染情况很常见,不过对该病原体的遗传多样性了解甚少。它是骆驼呼吸道正常菌群的一部分,但当骆驼身体抵抗力因恶劣生态条件而减弱时,它就会致病。本研究旨在检测、鉴定并确定在马萨比特县和图尔卡纳县感染骆驼的[病原体名称]的遗传多样性。KMT1基因被用作[病原体名称1]和[病原体名称2]的标记基因,而[其他基因名称1]、[其他基因名称2]、[其他基因名称3]、[其他基因名称4]和[其他基因名称5]分别作为荚膜血清群A、B、D、E和F的标记基因。在102份血液样本和30份鼻拭子样本中,有21份样本(16%)被确认为[病原体名称]阳性,且在两个县均仅检测到荚膜E群。[病原体名称]的序列高度保守,且与世界其他地区的菌株相关。我们的研究证实,肯尼亚马萨比特县和图尔卡纳县的骆驼感染了荚膜E型[病原体名称]。养殖户不应让骆驼吃不饱,应确保实施适当的药物治疗和疫苗接种计划,并尽量减少在拥挤地区(尤其是潮湿环境中)放牧骆驼,以减缓[病原体名称]感染的传播。