• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

银屑病治疗中的惰性:印度皮肤科医生和患者的定量调查

Therapeutic Inertia in the Management of Psoriasis: A Quantitative Survey Among Indian Dermatologists and Patients.

作者信息

Rajagopalan Murlidhar, Dogra Sunil, Godse Kiran, Kar Bikash Ranjan, Kotla Sai Krishna, Neema Shekhar, Saraswat Abir, Shah Swapnil Deepak, Madnani Nina, Sardesai Vidyadhar, Sekhri Rajiv, Varma Sachin, Arora Sandeep, Kawatra Pallavi

机构信息

Department of Dermatology, Apollo Hospital, Chennai, India.

Department of Dermatology Venereology & Leprology Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, 160012, India.

出版信息

Psoriasis (Auckl). 2022 Aug 25;12:221-230. doi: 10.2147/PTT.S375173. eCollection 2022.

DOI:10.2147/PTT.S375173
PMID:36046360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9423113/
Abstract

PURPOSE

The primary objective of the study was to understand the therapeutic inertia in treatment and management of plaque psoriasis among dermatologists, along with determining the preferred treatment choices for management of plaque psoriasis; it also included the resulting treatment satisfaction among patients. The secondary objective was to identify the gaps in terms of knowledge and attitude among dermatologists and the expectations of patients.

PATIENTS AND METHODS

A multicentre, cross-sectional quantitative survey was conducted among dermatologists and patients with moderate to severe plaque psoriasis across India. The interviews were conducted either face to face or via telephone between September and November 2020, using structured and validated questionnaires based on specific themes. The data obtained were statistically analysed, wherever applicable.

RESULTS

Overall, 207 adult patients with moderate-to-severe plaque psoriasis and 303 dermatologists were interviewed. Post experiencing symptoms, 44% of the patients visited general physicians for treatment and there was an average 7.8-month delay by the patients to consult a dermatologist. Approximately one-fourth of patients used home remedies before seeking medical help. One-third of dermatologists used the Psoriasis Area and Severity Index (PASI) for assessing the disease severity. Majority of dermatologists preferred combination therapy for their patients. The lack of quick resolution and side effects were the major reasons for changing the treatment. Overall, only 35% of the patients complied to current treatment. Satisfaction with existing forms of therapies was highest for mild plaque psoriasis (62%) as confirmed by dermatologists, while 52% of the overall patients were satisfied with their therapy. Majority of the patients (64%) affirmed living with plaque psoriasis impacted their lives.

CONCLUSION

This first-of-its-kind survey in India highlighted the gaps in terms of the disease journey between dermatologists and patients. The survey emphasises the need for shared decision-making and may benefit dermatologists in suggestive modifications of the treatment algorithm and disease management in clinical settings.

摘要

目的

本研究的主要目的是了解皮肤科医生在斑块状银屑病治疗和管理中的治疗惰性,同时确定斑块状银屑病管理的首选治疗方案;研究还包括患者由此产生的治疗满意度。次要目的是找出皮肤科医生在知识和态度方面的差距以及患者的期望。

患者与方法

在印度各地的皮肤科医生和中重度斑块状银屑病患者中进行了一项多中心横断面定量调查。2020年9月至11月期间,采用基于特定主题的结构化且经过验证的问卷,通过面对面或电话方式进行访谈。所获数据在适用时进行统计分析。

结果

总体而言,共访谈了207例中重度斑块状银屑病成年患者和303名皮肤科医生。出现症状后,44%的患者前往全科医生处治疗,患者咨询皮肤科医生的平均延迟时间为7.8个月。约四分之一的患者在寻求医疗帮助前使用过家庭疗法。三分之一的皮肤科医生使用银屑病面积和严重程度指数(PASI)评估疾病严重程度。大多数皮肤科医生倾向于为患者采用联合治疗。治疗缺乏快速缓解和副作用是改变治疗的主要原因。总体而言,只有35%的患者依从当前治疗。皮肤科医生证实,轻度斑块状银屑病患者对现有治疗方式的满意度最高(62%),而总体患者中有52%对其治疗感到满意。大多数患者(64%)确认斑块状银屑病影响了他们的生活。

结论

印度的这项首例调查凸显了皮肤科医生和患者在疾病诊疗过程中的差距。该调查强调了共同决策的必要性,可能有助于皮肤科医生在临床环境中对治疗算法和疾病管理进行有针对性的调整。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/9423113/f5f9a41a09ae/PTT-12-221-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/9423113/2faf7ce0df88/PTT-12-221-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/9423113/f5f9a41a09ae/PTT-12-221-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/9423113/2faf7ce0df88/PTT-12-221-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/9423113/f5f9a41a09ae/PTT-12-221-g0002.jpg

相似文献

1
Therapeutic Inertia in the Management of Psoriasis: A Quantitative Survey Among Indian Dermatologists and Patients.银屑病治疗中的惰性:印度皮肤科医生和患者的定量调查
Psoriasis (Auckl). 2022 Aug 25;12:221-230. doi: 10.2147/PTT.S375173. eCollection 2022.
2
Evolution of Patient Perceptions of Psoriatic Disease: Results from the Understanding Psoriatic Disease Leveraging Insights for Treatment (UPLIFT) Survey.银屑病患者认知的演变:利用治疗见解了解银屑病(UPLIFT)调查结果
Dermatol Ther (Heidelb). 2022 Jan;12(1):61-78. doi: 10.1007/s13555-021-00635-4. Epub 2021 Oct 25.
3
Defining and treating moderate plaque psoriasis: a dermatologist survey.定义和治疗中度斑块状银屑病:皮肤科医生调查
J Dermatolog Treat. 2018 Nov;29(7):658-663. doi: 10.1080/09546634.2018.1443200. Epub 2018 Mar 22.
4
Gaps in moderate plaque psoriasis management: A survey of Saudi dermatologists.中度斑块状银屑病治疗中的差距:沙特皮肤科医生的一项调查。
J Family Med Prim Care. 2021 Dec;10(12):4519-4524. doi: 10.4103/jfmpc.jfmpc_1207_21. Epub 2021 Dec 27.
5
Understanding Barriers Impacting upon Patient Wellbeing: A Nationwide Italian Survey and Expert Opinion of Dermatologists Treating Patients with Moderate-to-Severe Psoriasis.了解影响患者福祉的障碍:一项意大利全国性调查及治疗中重度银屑病患者的皮肤科医生的专家意见
J Clin Med. 2023 Dec 24;13(1):101. doi: 10.3390/jcm13010101.
6
Treatment adherence and real-life effectiveness of topical therapy in patients with mild or moderate psoriasis: uptake of scientific evidence in clinical practice and dermatologists' preferences for alternative treatment options.轻度或中度银屑病患者局部治疗的治疗依从性及实际疗效:临床实践中科学证据的应用及皮肤科医生对替代治疗方案的偏好
G Ital Dermatol Venereol. 2015 Feb;150(1):19-26. Epub 2014 Dec 18.
7
Experiences of Dermatologists and Patients Regarding Psoriasis and Its Connection to Psoriatic Arthritis in Saudi Arabia.沙特阿拉伯皮肤科医生和患者关于银屑病及其与银屑病关节炎关联的经历
Psoriasis (Auckl). 2024 Jan 18;14:11-22. doi: 10.2147/PTT.S427775. eCollection 2024.
8
Patient-reported outcomes are important elements of psoriasis treatment decision making: A discrete choice experiment survey of dermatologists in the United States.患者报告的结局是银屑病治疗决策的重要组成部分:美国皮肤科医生的离散选择实验调查。
J Am Acad Dermatol. 2019 Jun;80(6):1650-1657. doi: 10.1016/j.jaad.2019.01.039. Epub 2019 Jan 29.
9
A Survey of Treatment Practices in Management of Psoriasis Patients among Dermatologists of Kerala.喀拉拉邦皮肤科医生对银屑病患者治疗方法的调查
Indian Dermatol Online J. 2019 Jul-Aug;10(4):437-440. doi: 10.4103/idoj.IDOJ_306_18.
10
Dermatologists' Perspectives on Defining Moderate Psoriasis: The Canadian Moderate Psoriasis Survey.皮肤科医生对中度银屑病定义的看法:加拿大中度银屑病调查。
J Drugs Dermatol. 2021 Feb 1;20(2):126-132. doi: 10.36849/JDD.5531.

引用本文的文献

1
Patient perspective on psoriasis: Psychosocial burden of psoriasis and its management in Malaysia.患者对银屑病的看法:马来西亚银屑病的心理社会负担及其管理。
PLoS One. 2024 Jul 18;19(7):e0305870. doi: 10.1371/journal.pone.0305870. eCollection 2024.
2
Fabrication and characterization of apremilast-loaded zinc oxide-mesoporous silica nanoparticles for psoriasis treatment.阿普司特负载氧化锌介孔硅纳米粒的制备及性能评价及其在银屑病治疗中的应用。
Ther Deliv. 2024;15(6):449-462. doi: 10.1080/20415990.2024.2343646. Epub 2024 May 22.
3
Patient Perspectives of the Impact of Psoriatic Disease on Quality-of-Life in India: Sub-analysis from the Global Psoriasis and Beyond Survey.

本文引用的文献

1
Real-Life Effectiveness of Apremilast for the Treatment of Psoriasis in Belgium: Results From the Observational OTELO Study.比利时阿普米司特治疗银屑病的真实疗效:观察性 OTELO 研究结果。
Adv Ther. 2022 Feb;39(2):1068-1080. doi: 10.1007/s12325-021-01981-7. Epub 2022 Jan 3.
2
Evolution of Patient Perceptions of Psoriatic Disease: Results from the Understanding Psoriatic Disease Leveraging Insights for Treatment (UPLIFT) Survey.银屑病患者认知的演变:利用治疗见解了解银屑病(UPLIFT)调查结果
Dermatol Ther (Heidelb). 2022 Jan;12(1):61-78. doi: 10.1007/s13555-021-00635-4. Epub 2021 Oct 25.
3
Systemic Management of Psoriasis Patients in Indian Scenario: An Expert Consensus.
印度银屑病患者对银屑病疾病对生活质量影响的看法:全球银屑病及其他调查的子分析
Indian Dermatol Online J. 2024 Feb 28;15(2):233-241. doi: 10.4103/idoj.idoj_350_23. eCollection 2024 Mar-Apr.
印度银屑病患者的系统管理:专家共识
Indian Dermatol Online J. 2021 Sep 10;12(5):674-682. doi: 10.4103/idoj.IDOJ_113_21. eCollection 2021 Sep-Oct.
4
The Use of Apremilast in Psoriasis: An Indian Perspective on Real-World Scenarios.阿普米拉斯在银屑病治疗中的应用:印度对现实世界情况的看法。
Psoriasis (Auckl). 2021 Aug 14;11:109-122. doi: 10.2147/PTT.S320810. eCollection 2021.
5
Psoriasis.银屑病。
Lancet. 2021 Apr 3;397(10281):1301-1315. doi: 10.1016/S0140-6736(20)32549-6.
6
Pattern of use of biologics in psoriasis among Indian dermatologists - A cross sectional survey.印度皮肤科医生中生物制剂治疗银屑病的使用模式 - 一项横断面调查。
Indian J Dermatol Venereol Leprol. 2022 May-Jun;88(4):515-518. doi: 10.25259/IJDVL_1006_19.
7
Epidemiological survey of the psoriasis patients in the Japanese Society for Psoriasis Research from 2013 to 2018.2013 年至 2018 年日本银屑病研究学会银屑病患者的流行病学调查。
J Dermatol. 2021 Jun;48(6):864-875. doi: 10.1111/1346-8138.15803. Epub 2021 Feb 13.
8
National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study.银屑病的国家、地区和全球流行病学:系统分析和建模研究。
BMJ. 2020 May 28;369:m1590. doi: 10.1136/bmj.m1590.
9
Emerging systemic drugs in the treatment of plaque psoriasis.新兴的系统性药物治疗斑块型银屑病。
Expert Opin Emerg Drugs. 2020 Jun;25(2):89-100. doi: 10.1080/14728214.2020.1745773. Epub 2020 Mar 31.
10
Stigmatization and Quality of Life in Patients with Psoriasis.银屑病患者的污名化与生活质量
Dermatol Ther (Heidelb). 2020 Apr;10(2):285-296. doi: 10.1007/s13555-020-00363-1. Epub 2020 Mar 7.