Hernández-Herrera Jonathan Esaú, Sánchez-Pichardo Guillermo, Castruita-Torres Derión Sorokto Tsaraí, González-Peredo Adriana Iriancid, Acevedo-García Elia, Díaz-Murillo Teresa Andrea, Barrientos-Rodríguez Mayra Guadalupe, Cisneros-Carrasco Juan Manuel
Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades, Laboratorio de Análisis Clínicos. León, Guanajuato, México.
Servicios Integrales Nova de Monterrey, Hospital Clínica Nova/Ternium, Laboratorio de Análisis Clínicos. Monterrey, Nuevo Léon, México.
Rev Med Inst Mex Seguro Soc. 2022 Aug 31;60(5):503-510.
Antimicrobial resistance represents a serious public health problem that has caused an increase in the morbidity and mortality of infections, a greater use of antibiotics and excessive hospitalization costs.
To describe the frequency of Escherichia coli and its pattern of bacterial susceptibility in cultures of blood, urine and other body fluids in a tertiary care hospital.
A quantitative and retrospective test was designed to evaluate the sensitivity pattern of the data obtained in the Microbiology Department. Descriptive statistics were obtained from the sensitivity patterns of the microorganism studied in the period of time analyzed.
The sensitivity pattern of different samples evaluated in the unit (n = 694) was recovered. In the strains analyzed, it was found that about 50% have a positive phenotype for extended-spectrum beta-lactamases and that the sensitivity pattern shows that penicillins, cephalosporins and fluoroquinolones are not adequate antimicrobials to treat infections derived from this microorganism.
The antimicrobial pattern obtained demonstrates the imperative need for rational and well-founded use of antibiotic therapy, highlighted by the great difference with reports in other scientific articles. Investment in mechanisms to confirm these patterns is necessary, which is why no expense should be spared for the identification, typification and classification of disease-causing microorganisms.
抗菌药物耐药性是一个严重的公共卫生问题，已导致感染的发病率和死亡率上升、抗生素使用增加以及住院费用过高。
描述一家三级护理医院血液、尿液和其他体液培养物中大肠杆菌的频率及其细菌敏感性模式。
设计了一项定量回顾性试验，以评估微生物学部门获得的数据的敏感性模式。描述性统计数据来自于在分析时间段内所研究微生物的敏感性模式。
恢复了该科室评估的不同样本（n = 694）的敏感性模式。在所分析的菌株中，发现约50%具有超广谱β-内酰胺酶阳性表型，且敏感性模式表明青霉素、头孢菌素和氟喹诺酮类并非治疗源自该微生物感染的合适抗菌药物。
所获得的抗菌模式表明迫切需要合理且有充分依据地使用抗生素治疗，这一点在与其他科学文章中的报告存在巨大差异中得到凸显。有必要投入资源来确认这些模式，这就是为什么在致病微生物的鉴定、分型和分类上不应吝惜成本。
