School of Chemistry, Tiangong University, PR China; State Key Laboratory of Separation Membranes and Membrane Processes, Tianjin 300387, PR China.
School of Chemical Engineering and Technology, Tiangong University, PR China; State Key Laboratory of Separation Membranes and Membrane Processes, Tianjin 300387, PR China.
Bioorg Med Chem. 2022 Oct 15;72:116987. doi: 10.1016/j.bmc.2022.116987. Epub 2022 Aug 28.
With advances in nanotechnology and the development of emerging therapeutic modalities, a surge in research on the use of nanomedicines for biomedical applications has occurred over the past three decades. Carbon dots (CDs) are new members of carbon-based nanomaterials that can be used in cancer treatment to reduce side effects of drugs and improve treatment efficiency, offering new medical opportunities for further research. Urged as such, we are encouraged to classify CDs-based cancer treatments, including photodynamic therapy (PDT), photothermal therapy (PTT), sonodynamic therapy (SDT), chemodynamic therapy (CDT), chemotherapy (CT), and synergistic therapy. The advantages of these approaches are summarized, as well as ways to improve certain shortcomings. Meanwhile, this review highlights the feasible practice of CDs in cancer treatment, which is further developed and widely used in the biomedical field.
在纳米技术的进步和新兴治疗模式的发展下，过去三十年来，纳米医学在生物医学应用方面的研究呈激增态势。碳点（CDs）是碳基纳米材料的新成员，可用于癌症治疗以减少药物的副作用并提高治疗效率，为进一步研究提供了新的医学机会。因此，我们鼓励对基于 CDs 的癌症治疗进行分类，包括光动力疗法（PDT）、光热疗法（PTT）、声动力疗法（SDT）、化学动力学疗法（CDT）、化学疗法（CT）和协同疗法。总结了这些方法的优点，并提出了改进某些缺点的方法。同时，本文还强调了 CDs 在癌症治疗中的可行实践，这在生物医学领域得到了进一步的发展和广泛应用。
