Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA; Brawerman Nursing Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Emory University School of Medicine, Atlanta, Georgia, USA.
J Am Coll Cardiol. 2022 Sep 6;80(10):1014-1022. doi: 10.1016/j.jacc.2022.01.057.
The Cardiovascular Disease in Women Committee of the American College of Cardiology convened a working group to develop a consensus regarding the continuing rise of mortality rates in young women aged 35 to 54 years. Heart disease mortality rates in young women continue to increase. Young women have increased mortality secondary to ischemic heart disease (IHD) compared with comparably aged men and similar mortality to that observed among older women. The authors reviewed the published evidence, including observational and mechanistic/translational data, and identified knowledge gaps pertaining to young women. This paper provides clinicians with pragmatic, evidence-based management strategies for young women at risk for IHD. Next-step research opportunities are outlined. This report presents highlights of the working group review and a summary of suggested research directions to advance the IHD field in the next decade.
美国心脏病学会心血管疾病女性委员会召集了一个工作组，以就 35 至 54 岁年轻女性死亡率持续上升的问题达成共识。年轻女性的心脏病死亡率持续上升。与同龄男性相比，年轻女性因缺血性心脏病（IHD）导致的死亡率增加，与老年女性的死亡率相似。作者回顾了已发表的证据，包括观察性和机制/转化数据，并确定了与年轻女性相关的知识空白。本文为处于 IHD 风险中的年轻女性提供了实用的、基于证据的管理策略。下一步的研究机会也进行了概述。本报告介绍了工作组审查的要点，并提出了建议的研究方向，以在未来十年推进 IHD 领域的发展。
