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青年人心血管病预防和治疗的挑战与机遇:美国国家心肺血液研究所工作组的报告。

Challenges and Opportunities for the Prevention and Treatment of Cardiovascular Disease Among Young Adults: Report From a National Heart, Lung, and Blood Institute Working Group.

机构信息

Division of General Pediatrics and Adolescent Medicine Emory UniversityChildren's Healthcare of Atlanta Atlanta GA.

Genomic Medicine Institute Geisinger Danville PA.

出版信息

J Am Heart Assoc. 2020 Oct 20;9(19):e016115. doi: 10.1161/JAHA.120.016115. Epub 2020 Sep 30.

DOI:10.1161/JAHA.120.016115
PMID:32993438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7792379/
Abstract

Improvements in cardiovascular disease (CVD) rates among young adults in the past 2 decades have been offset by increasing racial/ethnic and gender disparities, persistence of unhealthy lifestyle habits, overweight and obesity, and other CVD risk factors. To enhance the promotion of cardiovascular health among young adults 18 to 39 years old, the medical and broader public health community must understand the biological, interpersonal, and behavioral features of this life stage. Therefore, the National Heart, Lung, and Blood Institute, with support from the Office of Behavioral and Social Science Research, convened a 2-day workshop in Bethesda, Maryland, in September 2017 to identify research challenges and opportunities related to the cardiovascular health of young adults. The current generation of young adults live in an environment undergoing substantial economic, social, and technological transformations, differentiating them from prior research cohorts of young adults. Although the accumulation of clinical and behavioral risk factors for CVD begins early in life, and research suggests early risk is an important determinant of future events, few trials have studied prevention and treatment of CVD in participants <40 years old. Building an evidence base for CVD prevention in this population will require the engagement of young adults, who are often disconnected from the healthcare system and may not prioritize long-term health. These changes demand a repositioning of existing evidence-based treatments to accommodate new sociotechnical contexts. In this article, the authors review the recent literature and current research opportunities to advance the cardiovascular health of today's young adults.

摘要

在过去的 20 年中,年轻人中心血管疾病(CVD)发病率的改善被不断扩大的种族/民族和性别差距、不健康生活方式习惯的持续存在、超重和肥胖以及其他 CVD 风险因素所抵消。为了促进 18 至 39 岁年轻人的心血管健康,医疗和更广泛的公共卫生界必须了解这个生命阶段的生物学、人际和行为特征。因此,美国国家心肺血液研究所(National Heart, Lung, and Blood Institute)在行为和社会科学研究办公室(Office of Behavioral and Social Science Research)的支持下,于 2017 年 9 月在马里兰州贝塞斯达召开了为期两天的研讨会,以确定与年轻人心血管健康相关的研究挑战和机遇。这一代年轻人生活在一个经历着巨大经济、社会和技术变革的环境中,与之前的年轻人研究队列有所不同。尽管 CVD 的临床和行为风险因素在生命早期就开始积累,而且研究表明早期风险是未来事件的重要决定因素,但很少有试验研究过<40 岁参与者的 CVD 预防和治疗。在这一人群中建立 CVD 预防的证据基础将需要年轻人的参与,他们通常与医疗保健系统脱节,可能并不优先考虑长期健康。这些变化要求将现有的基于证据的治疗方法重新定位,以适应新的社会技术背景。在本文中,作者回顾了最近的文献和当前的研究机会,以促进当今年轻人的心血管健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/6f741d6fc994/JAH3-9-e016115-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/a70eb57521b7/JAH3-9-e016115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/4ccb2ebcaab9/JAH3-9-e016115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/5e600e89ac26/JAH3-9-e016115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/6f741d6fc994/JAH3-9-e016115-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/a70eb57521b7/JAH3-9-e016115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/4ccb2ebcaab9/JAH3-9-e016115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/5e600e89ac26/JAH3-9-e016115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3943/7792379/6f741d6fc994/JAH3-9-e016115-g004.jpg

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