Central Virginia Veterans Affairs Medical Center, 1201 Broad Rock Blvd (111N), Richmond, VA 23249, USA.
Central Virginia Veterans Affairs Medical Center, 1201 Broad Rock Blvd (111N), Richmond, VA 23249, USA.
Crit Care Nurs Clin North Am. 2022 Sep;34(3):289-301. doi: 10.1016/j.cnc.2022.04.004. Epub 2022 Jul 20.
Hepatocellular carcinoma (HCC) is a primary liver malignancy commonly encountered in the setting of chronic liver disease and cirrhosis. Survival in HCC is determined by the ABCs: (A) anatomic stage; (B) biologic grade; and (C) cirrhosis severity. Improvement of imaging techniques permits clinicians to accurately diagnose HCC without biopsy confirmation. Advances in surgical and therapeutic options have improved treatment response and survival. Surgical resection, liver transplant, and thermal ablation in selected patients can potentially cure HCC. Noncurative approaches including intraarterial, radiation, and systemic therapies aim to palliate or slow the progression of disease. Management of HCC is complex, and the choice of treatment approach is enhanced by multidisciplinary consensus, including a liver transplant center.
肝细胞癌 (HCC) 是一种常见于慢性肝病和肝硬化背景下的原发性肝脏恶性肿瘤。HCC 的生存取决于 ABCs：(A) 解剖分期；(B) 生物学分级；和 (C) 肝硬化严重程度。影像学技术的改进使得临床医生无需活检即可准确诊断 HCC。手术和治疗选择的进步改善了治疗反应和生存。在选定的患者中，手术切除、肝移植和热消融术可能治愈 HCC。非治愈方法包括动脉内、放射和全身治疗，旨在缓解或减缓疾病进展。HCC 的管理很复杂，通过多学科共识（包括肝移植中心）可以增强治疗方法的选择。
