Suppr超能文献

小儿先天性心脏病手术中持续胸段硬膜外镇痛的快速康复:一项机构经验

Fast-tracking with continuous thoracic epidural analgesia in paediatric congenital heart surgeries: an institutional experience.

作者信息

Kumar Alok, Ramamurthy H R, Tiwari Nikhil, Joshi Saajan, Kumar Gaurav, Kumar Vivek, Sharma Vipul

机构信息

Department of Anaesthesia & Critical Care, Army Hospital (Research & Referral), Delhi Cantt, New Delhi 110010 India.

Department of Paediatrics, Army Hospital (Research & Referral), Delhi Cantt, New Delhi 110010 India.

出版信息

Indian J Thorac Cardiovasc Surg. 2022 Sep;38(5):469-480. doi: 10.1007/s12055-022-01373-8. Epub 2022 May 26.

Abstract

OBJECTIVE

To assess the success of fast-tracking in infants and small children undergoing paediatric cardiac surgery under general anaesthesia with continuous thoracic epidural analgesia (TEA).

METHODOLOGY

It is a retrospective study at a tertiary care hospital. A total of 461 children, aged 12 years or younger, were operated for congenital heart disease over a 2-year period from January 2018 to December 2019. After the exclusion of 71 patients, data from the remaining 390 patients were analysed.

MEASUREMENTS AND MAIN RESULTS

The median time for extubation after intensive care unit admission was 2 h and 25 min (0-20 h). Extubation within 6 h was achieved in 215 patients (~ 55%). Patients in the early extubation group had significantly shorter hospital stay (4.1 ± 2.3 vs 6.9 ± 3.9 days,  = 0.004) than patients in the ventilated group. Reintubation was required in 27 (6.9%) patients. Thirteen patients died postoperatively on ventilator. Patients with low nadir temperature intraoperatively and cardiopulmonary bypass time > 90 min significantly predicted failure in fast-tracking with an odds ratio (OR) = 1.27; CI: 1.18-1.38 and OR = 2.3; CI: 1.8-2.96 respectively. The Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery Congenital Heart Surgery mortality score, younger age, Down syndrome and high vasopressor inotropic score did not adversely affect early extubation, contrary to contemporary concerns.

CONCLUSIONS

A multimodal approach for perioperative pain relief and sedation consisting of propofol and dexmedetomidine infusion along with TEA ensures early extubation in 59% of the cases undergoing paediatric cardiac surgery. Our data suggests that fast-tracking is feasible with safe and superior outcomes in a subset of appropriate patients undergoing paediatric cardiac surgery.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s12055-022-01373-8.

摘要

目的

评估在全身麻醉联合持续胸椎硬膜外镇痛(TEA)下行小儿心脏手术的婴幼儿和儿童中实施快速康复的成效。

方法

这是一项在三级护理医院开展的回顾性研究。在2018年1月至2019年12月的2年期间,共有461名12岁及以下的儿童接受了先天性心脏病手术。排除71名患者后,对其余390名患者的数据进行了分析。

测量指标及主要结果

重症监护病房入院后拔管的中位时间为2小时25分钟(0 - 20小时)。215名患者(约55%)在6小时内实现了拔管。早期拔管组患者的住院时间显著短于通气组患者(4.1±2.3天 vs 6.9±3.9天,P = 0.004)。27名(6.9%)患者需要再次插管。13名患者术后在呼吸机辅助下死亡。术中最低体温低和体外循环时间>90分钟的患者显著预示快速康复失败,优势比(OR)分别为1.27;CI:1.18 - 1.38和OR = 2.3;CI:1.8 - 2.96。与当代担忧相反,胸外科医师协会 - 欧洲心胸外科学会先天性心脏病手术死亡率评分、年龄较小、唐氏综合征和高血管活性药物肌力评分并未对早期拔管产生不利影响。

结论

由丙泊酚和右美托咪定输注联合TEA组成的围手术期疼痛缓解和镇静多模式方法可确保59%的小儿心脏手术病例早期拔管。我们的数据表明,在一部分接受小儿心脏手术的合适患者中,快速康复是可行的,且具有安全和更好的结果。

补充信息

在线版本包含可在10.1007/s12055 - 022 - 01373 - 8获取的补充材料。

相似文献

3
Assessment of the factors that affect fast-track or early extubation following pediatric cardiac surgery.评估影响小儿心脏手术后快速通道或早期拔管的因素。
Turk Gogus Kalp Damar Cerrahisi Derg. 2023 Jan 30;31(1):1-7. doi: 10.5606/tgkdc.dergisi.2023.23206. eCollection 2023 Jan.
6
Fast-track cardiac care for adult cardiac surgical patients.成人心脏手术患者的快速心脏护理
Cochrane Database Syst Rev. 2016 Sep 12;9(9):CD003587. doi: 10.1002/14651858.CD003587.pub3.
7
Fast-track cardiac care for adult cardiac surgical patients.针对成年心脏外科手术患者的快速心脏护理
Cochrane Database Syst Rev. 2012 Oct 17;10:CD003587. doi: 10.1002/14651858.CD003587.pub2.

本文引用的文献

7
Extubation in the operating room after congenital heart surgery in children.小儿先天性心脏病手术后在手术室拔管
J Thorac Cardiovasc Surg. 2008 Jul;136(1):88-93. doi: 10.1016/j.jtcvs.2007.11.042. Epub 2008 May 27.
9
Extubation after cardiothoracic surgery in neonates, children, and young adults: One year of institutional experience.
Pediatr Crit Care Med. 2007 Nov;8(6):552-555. doi: 10.1097/01.PCC.0000282174.37595.4C.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验