Ravandi Fatemeh, Haj Mohamad Ebrahim Ketabforoush Arsh, Azedi Fereshteh, Hoshyarkhani Mohsen, Fayyaz Farimah, Abbasi Khoshsirat Nahid
Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Cellular & Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Neurol Res Int. 2022 Aug 24;2022:7348505. doi: 10.1155/2022/7348505. eCollection 2022.
Since heart failure (HF) and ischemic stroke have common risk factors, their concurrent occurrence is likely. Strokes in HF patients could be life-threatening and lead to severe disabilities, longer hospitalization time, and mortality. The present study aims to investigate the prevalence of HF and its severity based on ejection fraction (EF) in patients with acute ischemic stroke.
The present cross-sectional study included acute ischemic stroke patients admitted to Shahid Rajaei hospital in Karaj in 2020-2021. The diagnosis of HF was based on transthoracic echocardiography within 48 hours of symptom onset, and HF was classified into two groups: 41-49% as mildly reduced EF (HFmrEF) and ≤40% as reduced EF (HFrEF). Patients who did not complete cardiac studies were excluded.
257 acute ischemic stroke patients (62.6% male) were included. Among stroke patients, the prevalence of HF, including HFrEF and HFmrEF, was 30.0% (95% CI: 21.4-38.6). HFmrEF and HFrEF was diagnosed in 32 (12.5%) and 45 (17.5%) patients, respectively. HF was significantly associated with older age, hypertension, past myocardial infarction (MI), and arrhythmia. A history of previous MI significantly increased the odds of heart failure (OR: 3.25, 95% CI: 1.82-5.81).
There is a high prevalence of HF among acute ischemic stroke patients. Older patients with a history of hypertension and previous MI are at higher risk. Since patients with HF have a higher mortality and morbidity rate after experiencing an ischemic stroke, close cooperation between the neurology and cardiology specialists for providing advanced care for survivors is required.
由于心力衰竭（HF）和缺血性中风有共同的危险因素，它们可能同时发生。心力衰竭患者发生中风可能危及生命，并导致严重残疾、住院时间延长和死亡。本研究旨在调查急性缺血性中风患者中HF的患病率及其基于射血分数（EF）的严重程度。
本横断面研究纳入了2020 - 2021年在卡拉季的沙希德拉贾伊医院住院的急性缺血性中风患者。HF的诊断基于症状发作后48小时内的经胸超声心动图检查，HF分为两组：EF为41 - 49%为轻度降低的EF（HFmrEF），EF≤40%为降低的EF（HFrEF）。未完成心脏检查的患者被排除。
纳入了257例急性缺血性中风患者（男性占62.6%）。在中风患者中，包括HFrEF和HFmrEF在内的HF患病率为30.0%（95%CI：21.4 - 38.6）。分别有32例（12.5%）和45例（17.5%）患者被诊断为HFmrEF和HFrEF。HF与老年、高血压、既往心肌梗死（MI）和心律失常显著相关。既往MI病史显著增加了心力衰竭的几率（OR：3.25，95%CI：1.82 - 5.81）。
急性缺血性中风患者中HF的患病率很高。有高血压和既往MI病史的老年患者风险更高。由于HF患者在发生缺血性中风后有更高的死亡率和发病率，因此神经内科和心内科专家需要密切合作，为幸存者提供高级护理。
