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口服甲芬那酸引起的固定性药疹——对用于缓解痛经的非处方药的药物不良反应。

Oral fixed drug eruptions to mefenamic acid - adverse drug reaction to over the counter medication taken for menstrual pain.

作者信息

Palla Santosh, Sajan Anand G, Sethuraman Vijayparthiban

机构信息

Oral Medicine and Radiology, Sun Dental Care, Tamil Nadu, India.

Oral and Maxillofacial Surgery, KIMS Dental College and Hospital, Amalapuram, India.

出版信息

Med Pharm Rep. 2022 Jul;95(3):348-351. doi: 10.15386/mpr-2325. Epub 2022 Jul 26.

Abstract

The reports on adverse drug reactions(ADR) to self-medication or over-the-counter medication are common across medical literature. However, the occurrence of oral fixed drug eruptions (FDE) to mefenamic acid is unique. We report a case of FDE to a drug obtained over the counter for menstrual pain. The essential findings from history, oral/dental examination, diagnostic approach, and treatment are briefly discussed along with a note on time and dosing for the oral drug provocation tests. The occurrence of ADR may be avoided by spreading awareness against OTC medication and labeling the specific drug for patients with established ADR.

摘要

关于自我用药或非处方药的药物不良反应(ADR)报告在医学文献中很常见。然而,甲芬那酸引起的口腔固定性药疹(FDE)却很独特。我们报告了一例因非处方购买用于缓解痛经的药物而引发FDE的病例。简要讨论了病史、口腔/牙科检查、诊断方法和治疗的主要发现,以及关于口服药物激发试验的时间和剂量的说明。通过提高对非处方药的认识并为已确诊ADR的患者标记特定药物,可以避免ADR的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e82/9387579/abf8f6486f4b/cm-95-348f1.jpg

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