Joshi Supriya, Singh Swati, Sharma Rimjhim, Vats Sharad, Alam Afroz
Department of Bioscience and Biotechnology, Banasthali Vidyapith, Tonk, Rajasthan 304022 India.
Vegetos. 2023;36(1):87-92. doi: 10.1007/s42535-022-00458-4. Epub 2022 Aug 30.
The bryophytes consist of liverworts, mosses, and hornworts, among which the liverworts are quite different in having cellular oil bodies and contain numerous terpenoids, acetogenins, quinones, phenylpropanoids, flavonoids, etc. These metabolites exhibit interesting biological activity such as allergenic response, insecticide, cytotoxic, neurotrophic, antimicrobial, and anti-HIV actions, etc. Though several bioactive compounds have been isolated in many liverworts, yet most of the liverworts have been unexplored till date regarding their phytochemistry. The ability of liverworts to generate a wide range of important phytochemicals makes them a hoard of bioactive compounds. In the past, a few species of bryophytes have been evaluated against a few viruses and interesting results were obtained that showed their role as an immunity enhancer against viral infection. The phytoconstituents found in liverworts and mosses can be useful to increase human immunity against a variety of viruses, including SARS-CoV-2. Keeping this in view, one of the most developed and robust metabolomics technologies, Gas chromatography-mass spectroscopy (GC-MS) was used to estimate the various phytoconstituents found in a commonly growing thalloid liverwort, and moss . The obtained profiles were appraised for their bioactive potential and probable role as antiviral agents.
苔藓植物包括叶苔、苔藓和角苔，其中叶苔有显著差异，具有细胞油体，并含有多种萜类化合物、产乙酸素、醌类、苯丙素类、黄酮类等。这些代谢产物表现出有趣的生物活性，如过敏反应、杀虫、细胞毒性、神经营养、抗菌和抗HIV作用等。虽然在许多叶苔中已分离出几种生物活性化合物，但迄今为止，大多数叶苔的植物化学性质仍未被探索。叶苔产生多种重要植物化学物质的能力使其成为生物活性化合物的宝库。过去，已对几种苔藓植物针对几种病毒进行了评估，并获得了有趣的结果，表明它们作为抗病毒感染的免疫增强剂的作用。在叶苔和苔藓中发现的植物成分可能有助于提高人类对包括SARS-CoV-2在内的多种病毒的免疫力。鉴于此，最发达、最强大的代谢组学技术之一——气相色谱-质谱联用（GC-MS）被用于评估一种常见的叶状体叶苔和苔藓中发现的各种植物成分。对获得的图谱进行了生物活性潜力评估以及作为抗病毒剂的可能作用评估。
