• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments.

作者信息

Vollert Jan, Macleod Malcolm, Dirnagl Ulrich, Kas Martien J, Michel Martin C, Potschka Heidrun, Riedel Gernot, Wever Kimberley E, Würbel Hanno, Steckler Thomas, Rice Andrew S C

机构信息

Pain Research, Department of Surgery and Cancer, Imperial College London, London, UK.

Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Kiel, Germany.

出版信息

Nat Methods. 2022 Nov;19(11):1334-1337. doi: 10.1038/s41592-022-01615-y.

DOI:10.1038/s41592-022-01615-y
PMID:36064774
Abstract
摘要

相似文献

1
The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments.用于动物实验设计、实施、分析和记录的严格性的EQIPD框架。
Nat Methods. 2022 Nov;19(11):1334-1337. doi: 10.1038/s41592-022-01615-y.
2
Refinement of experimental design and conduct in laboratory animal research.实验设计的优化与实验动物研究中的实施
ILAR J. 2014;55(3):383-91. doi: 10.1093/ilar/ilu037.
3
Improving the conduct, reporting, and appraisal of animal research.改进动物研究的实施、报告与评估。
BMJ. 2018 Jan 10;360:j4935. doi: 10.1136/bmj.j4935.
4
The EQIPD quality system - Assessment and certification procedures.EQIPD 质量体系——评估和认证程序。
J Neurosci Methods. 2024 Mar;403:110053. doi: 10.1016/j.jneumeth.2023.110053. Epub 2023 Dec 30.
5
The usefulness of systematic reviews of animal experiments for the design of preclinical and clinical studies.动物实验系统评价对临床前和临床研究设计的有用性。
ILAR J. 2014;55(3):427-37. doi: 10.1093/ilar/ilu043.
6
The place of experimental design and statistics in the 3Rs.实验设计与统计学在3R原则中的地位。
ILAR J. 2014;55(3):477-85. doi: 10.1093/ilar/ilu044.
7
Contribution of the Breadth and Depth of IACUC Membership to Experimental Design as a Factor in Research Reproducibility.机构动物护理与使用委员会（IACUC）成员的广度和深度对实验设计的贡献作为研究可重复性的一个因素
J Am Assoc Lab Anim Sci. 2018 Mar 1;57(2):104-109.
8
The '3Is' of animal experimentation.动物实验的“三 I”原则。
Nat Genet. 2012 May 29;44(6):611. doi: 10.1038/ng.2322.
9
We are not born knowing how to design and analyse scientific experiments.我们并非生来就知道如何设计和分析科学实验。
Altern Lab Anim. 2013 May;41(2):P19-21. doi: 10.1177/026119291304100212.
10
The Symbiotic Relationship Between Scientific Quality and Animal Research Ethics.科学质量与动物研究伦理之间的共生关系。
ILAR J. 2021 Sep 24;60(3):334-340. doi: 10.1093/ilar/ilab023.

引用本文的文献

1
Testing the usefulness of a quality system in preclinical research.测试质量体系在临床前研究中的实用性。
Neurosci Appl. 2024 Nov 13;4:105395. doi: 10.1016/j.nsa.2024.105395. eCollection 2025.
2
A companion to the preclinical common data elements for rigor, reproducibility and transparency in basic and translational epilepsy research. A report of the TASK3-WG1A: Pharmacology Working Group of the ILAE/AES Joint Translational Task Force.《临床前常见数据元素助力基础及转化性癫痫研究的严谨性、可重复性和透明度》。国际抗癫痫联盟/美国癫痫学会联合转化任务组TASK3-WG1A：药理学工作组报告。
Epilepsia Open. 2025 Aug;10 Suppl 1(Suppl 1):S18-S39. doi: 10.1002/epi4.70053. Epub 2025 Jun 26.
3

本文引用的文献

1
Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals.对涉及实验动物的临床前生物医学实验设计、实施及分析中内部有效性指南的系统评价。
BMJ Open Sci. 2020 Apr 15;4(1):e100046. doi: 10.1136/bmjos-2019-100046. eCollection 2020.
2
Investigating the replicability of preclinical cancer biology.探究癌症生物学的临床前可重复性。
Elife. 2021 Dec 7;10:e71601. doi: 10.7554/eLife.71601.
3
PEERS - An Open Science "Platform for the Exchange of Experimental Research Standards" in Biomedicine.
The Innovative Health Initiative public-private partnership: a catalyst for big data-driven health research and innovation.
创新健康倡议公私合作伙伴关系：大数据驱动的健康研究与创新的催化剂。
Front Med (Lausanne). 2025 Apr 1;12:1554948. doi: 10.3389/fmed.2025.1554948. eCollection 2025.
4
Enhanced BDNF and ROS in Mucosa of Lower Motor Neuron Lesioned Dog Bladder Following Somatic Motor Nerve Transfer.躯体运动神经转移后下运动神经元损伤犬膀胱黏膜中脑源性神经营养因子和活性氧增强
Cells. 2025 Mar 11;14(6):406. doi: 10.3390/cells14060406.
5
Evaluation of variation in preclinical electroencephalographic (EEG) spectral power across multiple laboratories and experiments: An EQIPD study.临床前脑电图（EEG）频谱功率在多个实验室和实验中的变异性评估：EQIPD 研究。
PLoS One. 2024 Oct 29;19(10):e0309521. doi: 10.1371/journal.pone.0309521. eCollection 2024.
6
An interdisciplinary perspective on peripheral drivers of pain in rheumatoid arthritis.类风湿关节炎外周驱动因素的跨学科视角。
Nat Rev Rheumatol. 2024 Nov;20(11):671-682. doi: 10.1038/s41584-024-01155-z. Epub 2024 Sep 6.
7
Dexmedetomidine on the interplay of IL-6 and STAT3 pathways in adrenal gland damage-induced scalding burns in rats.右美托咪定对大鼠肾上腺损伤所致烫伤中白细胞介素-6和信号转导与转录激活因子3通路相互作用的影响
Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan;398(1):641-655. doi: 10.1007/s00210-024-03300-7. Epub 2024 Jul 23.
8
Effects of a proprietary mixture of extracts from fruits and roots (WS 1541) on prostate hyperplasia and inflammation in rats and human cells.一种水果和根部提取物的专利混合物（WS 1541）对大鼠和人类细胞前列腺增生及炎症的影响。
Front Pharmacol. 2024 Mar 15;15:1379456. doi: 10.3389/fphar.2024.1379456. eCollection 2024.
9
Secondary Ischemia Assessment in Murine and Rat Preclinical Subarachnoid Hemorrhage Models: A Systematic Review.鼠类蛛网膜下腔出血模型中二级缺血评估的系统评价。
J Am Heart Assoc. 2024 Mar 5;13(5):e032694. doi: 10.1161/JAHA.123.032694. Epub 2024 Feb 29.
10
Spontaneous activity in peripheral sensory nerves: a systematic review.周围感觉神经的自发性活动：系统评价。
Pain. 2024 May 1;165(5):983-996. doi: 10.1097/j.pain.0000000000003115. Epub 2023 Nov 22.
PEERS——生物医学领域一个开放科学的“实验研究标准交流平台”。
Front Behav Neurosci. 2021 Oct 21;15:755812. doi: 10.3389/fnbeh.2021.755812. eCollection 2021.
4
Introduction to the EQIPD quality system.EQIPD 质量体系简介。
Elife. 2021 May 24;10:e63294. doi: 10.7554/eLife.63294.
5
Pseudoreplication in physiology: More means less.生理学中的伪重复：越多意味着越少。
J Gen Physiol. 2021 Feb 1;153(2). doi: 10.1085/jgp.202012826.
6
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research.ARRIVE 指南 2.0：报告动物研究的更新指南。
PLoS Biol. 2020 Jul 14;18(7):e3000410. doi: 10.1371/journal.pbio.3000410. eCollection 2020 Jul.
7
Preregistration of exploratory research: Learning from the golden age of discovery.探索性研究的预先注册：从发现的黄金时代中学习。
PLoS Biol. 2020 Mar 26;18(3):e3000690. doi: 10.1371/journal.pbio.3000690. eCollection 2020 Mar.
8
Mouse microbiomes: overlooked culprits of experimental variability.小鼠微生物组：实验变异性被忽视的罪魁祸首。
Genome Biol. 2019 May 29;20(1):108. doi: 10.1186/s13059-019-1723-2.
9
FAIRsharing as a community approach to standards, repositories and policies.FAIRsharing作为一种针对标准、存储库和政策的社区方法。
Nat Biotechnol. 2019 Apr;37(4):358-367. doi: 10.1038/s41587-019-0080-8.
10
Scientists rise up against statistical significance.科学家们奋起反对统计显著性。
Nature. 2019 Mar;567(7748):305-307. doi: 10.1038/d41586-019-00857-9.