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Papain as a Potential New Experimental Model of Non-histaminergic Itch.

作者信息

Aliotta Giulia Erica, Saii Zeinab, Elberling Jesper, Arendt-Nielsen Lars, Lo Vecchio Silvia

机构信息

Center for Neuroplasticity and Pain (CNAP), SMI, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Fredrik Bajers Vej 7D, D3-217, DK-9220 Aalborg East, Denmark.

出版信息

Acta Derm Venereol. 2022 Oct 4;102:adv00786. doi: 10.2340/actadv.v102.2693.

DOI:10.2340/actadv.v102.2693
PMID:36065741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9677266/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b86/9677266/48beaf310ac7/ActaDV-102-2693-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b86/9677266/48beaf310ac7/ActaDV-102-2693-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b86/9677266/48beaf310ac7/ActaDV-102-2693-g001.jpg

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本文引用的文献

1
Alloknesis and hyperknesis-mechanisms, assessment methodology, and clinical implications of itch sensitization.瘙痒致敏的感觉适应和超敏现象机制、评估方法学及临床意义。
Pain. 2018 Jul;159(7):1185-1197. doi: 10.1097/j.pain.0000000000001220.
2
TRPs and pain.瞬时受体电位通道与疼痛。
Semin Immunopathol. 2016 May;38(3):277-91. doi: 10.1007/s00281-015-0526-0. Epub 2015 Sep 15.
3
Human surrogate models of histaminergic and non-histaminergic itch.组胺能和非组胺能瘙痒的人体替代模型。
Acta Derm Venereol. 2015 Sep;95(7):771-7. doi: 10.2340/00015555-2146.
4
Three functionally distinct classes of C-fibre nociceptors in primates.灵长类动物中三种功能不同的C类纤维伤害感受器。
Nat Commun. 2014 Jun 20;5:4122. doi: 10.1038/ncomms5122.
5
Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis.蛋白酶和蛋白酶激活受体-2 在特应性皮炎发病机制中的作用。
Yonsei Med J. 2010 Nov;51(6):808-22. doi: 10.3349/ymj.2010.51.6.808.
6
Plant cysteine proteases that evoke itch activate protease-activated receptors.植物半胱氨酸蛋白酶诱发瘙痒，激活蛋白酶激活受体。
Br J Dermatol. 2010 Sep;163(3):532-5. doi: 10.1111/j.1365-2133.2010.09862.x. Epub 2010 Aug 12.
7
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms.表达瞬时受体电位香草酸亚型1（TRPV1）的初级传入神经通过多种机制对致痒原产生行为反应。
Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11330-5. doi: 10.1073/pnas.0905605106. Epub 2009 Jun 29.
8
Psychophysical and physiological evidence for parallel afferent pathways mediating the sensation of itch.介导瘙痒感觉的平行传入通路的心理物理学和生理学证据。
J Neurosci. 2007 Jul 11;27(28):7490-7. doi: 10.1523/JNEUROSCI.1249-07.2007.
9
Clinical classification of itch: a position paper of the International Forum for the Study of Itch.瘙痒的临床分类：国际瘙痒研究论坛立场文件
Acta Derm Venereol. 2007;87(4):291-4. doi: 10.2340/00015555-0305.
10
Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin.蛋白酶激活受体-2介导瘙痒：人类皮肤瘙痒的新途径。
J Neurosci. 2003 Jul 16;23(15):6176-80. doi: 10.1523/JNEUROSCI.23-15-06176.2003.