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多节段脊髓型颈椎病前路颈椎间盘切除术后两种不同固定方式的随机对照研究。

A randomized controlled study of two different fixations in anterior cervical discectomy of multilevel cervical spondylotic myelopathy.

机构信息

Department of Spinal Surgery, Huzhou Central Hospital, Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, China.

出版信息

J Orthop Surg (Hong Kong). 2022 Sep-Dec;30(3):10225536221118601. doi: 10.1177/10225536221118601.

Abstract

To compare the efficacy of anterior cervical discectomy and hybrid fusion (ACDHF) with short-segment plate plus self-locking, stand-alone intervertebral cages versus traditional anterior cervical discectomy and fusion (ACDF) with long-segment plate for multilevel cervical spondylotic myelopathy (MCSM). All the patients were randomly divided into two groups. 30 cases underwent ACDHF with short-segment plate and self-locking stand-alone cages (hybrid group), while the other 30 cases received ACDF with long-segment plate (control group). In patients meeting the inclusion and exclusion criteria, operation time, blood loss, postoperative drainage volume, length of stay (LOS), visual analogue scale for neck pain (VASNP) scores, Japanese Orthopaedic Association (JOA) score, and the cervical lordosis before and after the operation (5 days, 3, 6, 12 months after operation and final follow-up) were evaluated. The postoperative complications were analyzed as well. All operations were performed uneventfully with followed-up. Compared with ACDF, ACDHF showed a shorter operation time, less intraoperative blood loss and postoperative drainage ( < 0.05). There were no significant difference in LOS between two groups ( ˃ 0.05). Both approaches significantly improved the JOA scores, VASNP scores and the cervical lordosis ( < 0.05). Based on Bazaz grading system, hybrid group had a lower incidence of dysphagia than control group in follow-up periods of 5 days, 3 and 6 months ( < 0.05). ACDF and ACDHF are both effective methods of restoring cervical lordosis following MCSM, but hybrid surgery minimizes intraoperative injury and postoperative dysphagia, making it a viable treatment option for the disorder.

摘要

比较前路颈椎间盘切除融合术(ACDHF)联合短节段钢板及自锁式椎间融合器与传统前路颈椎间盘切除融合术(ACDF)联合长节段钢板治疗多节段脊髓型颈椎病(MCSM)的疗效。所有患者均随机分为两组。30 例患者行 ACDHF 联合短节段钢板及自锁式椎间融合器(杂交组),30 例患者行 ACDF 联合长节段钢板(对照组)。在符合纳入和排除标准的患者中,评估手术时间、出血量、术后引流量、住院时间(LOS)、颈痛视觉模拟评分(VASNP)评分、日本骨科协会(JOA)评分以及手术前后的颈椎前凸角(术后 5 天、3 个月、6 个月、12 个月及末次随访)。分析术后并发症。所有手术均顺利进行,随访。与 ACDF 相比,ACDHF 手术时间更短,术中出血量和术后引流量更少(<0.05)。两组 LOS 差异无统计学意义(>0.05)。两种方法均显著改善 JOA 评分、VASNP 评分和颈椎前凸角(<0.05)。根据 Bazaz 分级系统,杂交组在随访 5 天、3 个月和 6 个月时吞咽困难的发生率低于对照组(<0.05)。ACDF 和 ACDHF 都是治疗 MCSM 后恢复颈椎前凸的有效方法,但杂交手术术中损伤小,术后吞咽困难发生率低,是治疗该病的一种可行方法。

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