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颈椎间盘置换术与混合手术治疗脊髓型颈椎病矢状位序列及临床疗效:一项回顾性研究

Sagittal sequence and clinical efficacy of cervical disc replacement and hybrid surgery in the treatment of cervical spondylotic myelopathy: a retrospective study.

作者信息

Zheng Bin, Xu Shuai, Lu Tianliang, Wu Yonghao, Li Haoyuan, Guo Chen, Haiying Liu

机构信息

Spine Surgery Department, Peking University People's Hospital, Beijing, China.

Orthopedics Department, The Coal Central Hospital of Shanxi Province, Taiyuan, Shanxi, China.

出版信息

Front Surg. 2024 Jan 5;10:1265349. doi: 10.3389/fsurg.2023.1265349. eCollection 2023.

Abstract

BACKGROUND

Hybrid surgery (HS) combines anterior cervical discectomy and fusion (ACDF) with cervical disc replacement (CDR) is gradually being more frequently implemented, but there are few studies reporting the safety and effectiveness of hybrid surgery in three levels cervical spondylotic myelopathy.

METHODS

The clinical and radiographic data of patients with three-segment cervical spondylosis, who underwent CDR, ACDF and HS in our hospital from February 2007 to February 2013 were analyzed. The Visual Analog Scale (VAS), Japanese Orthopedic Association (JOA) and Neck Disability Index (NDI) were used to evaluate the clinical efficacy post surgery. Cervical spine x-rays were conducted to assess ROM, CL, T1S and relevant outcomes.

RESULTS

A total of 94 patients were included in the study: 26 in the CDR group, 13 in the HS1 group, 31 in the HS2 group, and 24 in the ACDF group. Most patients in the CDR group were younger. There was no difference in the follow-up duration, blood loss volume or surgery time ( > 0.05). Four groups reported improvements in JOA and NDI scores compared to baseline. There was no significant difference in the final JOA, final NDI or recovery rate among the 4 groups. The final ROM was smaller in the ACDF group than in the other 3 groups. There was no difference among the four groups in the final UROM, final LROM or their changes. There was no difference in the final T1S, final SVA or their change among the four groups. All groups showed similar changes in CL and T1S-CL.

CONCLUSIONS

There was no difference in the clinical outcomes of ACDF, CDR, or hybrid surgery. CDR can better preserve the mobility of the cervical spine. Neither CDR nor hybrid surgery was significantly advantageous over ACDF in restoring the sagittal sequence in patients with three-level CSM.

摘要

背景

混合手术(HS)将颈椎前路椎间盘切除切除切除术切除融合术(ACDF)与颈椎间盘置换术(CDR)相结合,其应用正逐渐增多,但很少有研究报道混合手术治疗三节段脊髓型颈椎病的安全性和有效性。

方法

分析2007年2月至2013年2月在我院接受CDR、ACDF和HS治疗的三节段颈椎病患者的临床和影像学资料。采用视觉模拟评分法(VAS)、日本骨科协会(JOA)评分和颈部功能障碍指数(NDI)评估术后临床疗效。通过颈椎X线检查评估活动度(ROM)、颈椎曲度(CL)、T1倾斜角(T1S)及相关结果。

结果

本研究共纳入94例患者:CDR组26例,HS1组13例,HS2组31例,ACDF组24例。CDR组大多数患者年龄较轻。随访时间、失血量或手术时间差异无统计学意义(P>0.05)。与基线相比,四组患者的JOA和NDI评分均有所改善。四组患者最终的JOA评分、最终的NDI评分或恢复率差异无统计学意义。ACDF组最终的ROM小于其他三组。四组患者最终的上位活动度(UROM)、最终的下位活动度(LROM)及其变化差异无统计学意义。四组患者最终的T1S、最终的矢状面垂直轴(SVA)及其变化差异无统计学意义。所有组的CL和T1S-CL变化相似。

结论

ACDF、CDR或混合手术的临床疗效无差异。CDR能更好地保留颈椎活动度。在恢复三节段脊髓型颈椎病患者矢状位序列方面,CDR和混合手术均未显示出明显优于ACDF的优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd3/10797051/668bd3fefa88/fsurg-10-1265349-g001.jpg

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