Bremmer Felix, Fichtner Alexander, Richter Annika, Schweyer Stefan
Institut für Pathologie, Universitätsmedizin Göttingen, 37075, Göttingen, Deutschland.
Gemeinschaftspraxis Pathologie Starnberg, Starnberg, Deutschland.
Pathologie (Heidelb). 2022 Nov;43(6):425-433. doi: 10.1007/s00292-022-01103-2. Epub 2022 Sep 7.
The great variety of pathological patterns in germ cell tumours, especially in yolk sac tumours but also the possibility of somatic-type malignancies, can complicate daily diagnosis. For the correct diagnosis, knowledge of morphological aspects and additional immunohistochemical staining can be helpful. Also, rare entities like sex cord stromal tumours, tumours of testicular adnexa or mesenchymal tumours of the spermatic cord can be diagnostically challenging.
生殖细胞肿瘤中存在多种病理模式，尤其是卵黄囊瘤，同时也存在发生体细胞型恶性肿瘤的可能性，这会使日常诊断变得复杂。为了做出正确诊断，了解形态学特征以及进行额外的免疫组化染色可能会有所帮助。此外，诸如性索间质肿瘤、睾丸附件肿瘤或精索间质肿瘤等罕见实体在诊断上也具有挑战性。
