Molecular Engineering, Biotechnology and Innovation Team, Geo-Bio -Environment Engineering and Innovation Laboratory, Polydisciplinary Faculty of Taroudant, IBN ZOHR University, Hay El Mohammadi (Lastah) B.P: 271, 83000, Taroudannt City, Morocco.
Regional Oncology Center, Souss Massa Region, Agadir city, Morocco.
Med Oncol. 2022 Sep 7;39(12):197. doi: 10.1007/s12032-022-01804-x.
Breast Cancer remains, according to the World Health Organization, the most complex disease cancer in 2021 in the world and the most common cause of death among women. Based on unequivocal scientific data, the establishment of an operative program for prevention could save lives of millions women suffering from breast cancer. In this update review, we highlight the major risk factors related to breast cancer investigated in women over the last 5 years. Thus, we clarify the involvement of these risk factors in the occurrence and growth of breast cancer. Investigations of 15 studies (n = 1,254,418; six case-control studies, five cohort studies, three prospective studies, and one meta-analysis) revealed that age, family history, obesity, use of oral contraceptives, status menopausal, smoking, alcohol consumption, lifestyle, and genetics factors are significantly linked to breast cancer. Additional studies are needed to corroborate these outcomes and initiate new practices aimed at preventing breast cancer.
根据世界卫生组织的数据,乳腺癌仍然是 2021 年全球最复杂的癌症疾病,也是女性死亡的最常见原因。基于明确的科学数据,制定一个预防性的手术方案可以挽救数以百万计患有乳腺癌的女性的生命。在本次更新综述中,我们重点介绍了过去 5 年来在女性中研究的与乳腺癌相关的主要危险因素。因此,我们阐明了这些危险因素在乳腺癌发生和发展中的作用。对 15 项研究(n=1254418;6 项病例对照研究、5 项队列研究、3 项前瞻性研究和 1 项荟萃分析)的调查显示,年龄、家族史、肥胖、口服避孕药的使用、绝经状态、吸烟、饮酒、生活方式和遗传因素与乳腺癌显著相关。需要进一步的研究来证实这些结果,并开展新的实践,以预防乳腺癌。