College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. China.
Parasitology. 2022 Oct;149(12):1652-1665. doi: 10.1017/S0031182022001196. Epub 2022 Aug 24.
spp. are important pathogens with some species causing diarrhoea in humans and animals. Sheep are one of the most common potential hosts for various spp. The prevalence of in sheep globally was evaluated from published information including molecular data via meta-analysis. In total, 126 datasets from 41 countries were included for final quantitative analysis. Sheep aged <3 months had a significantly higher prevalence (27.8%; 3284/11 938) than those at the age of 3–12 and >12 months. The prevalence of in sheep with diarrhoea of 35.4% (844/1915) was higher than in sheep that did not show diarrhoea (11.3%; 176/1691). Fourteen species/genotypes were detected in sheep globally. The proportion of subgenotype family XIIa of was 90.0% (216/240); the proportions of subgenotypes IIdA20G1 and IIaA15G2R1 of were 15.4% (62/402) and 19.7% (79/402). The results indicate that is the dominant species in Europe while is the dominant species in Oceania, Asia and Africa and is the dominant species in North America and South America. Subgenotype family IIa of is particularly widespread among sheep worldwide. The results highlight the role of sheep as a reservoir host for zoonotic cryptosporidia and the need for further study of prevalence, transmission and control of this pathogen in sheep.
种是重要的病原体，有些种可引起人和动物腹泻。绵羊是多种种的常见潜在宿主之一。通过荟萃分析，从已发表的信息（包括分子数据）评估了全球绵羊中种的流行情况。共有来自 41 个国家的 126 个数据集纳入最终的定量分析。<3 月龄的绵羊比 3-12 月龄和>12 月龄的绵羊具有更高的流行率（27.8%；3284/11938）。腹泻绵羊的流行率为 35.4%（844/1915），高于无腹泻绵羊的流行率（11.3%；176/1691）。全球绵羊中检测到 14 种/基因型。种的亚基因型家族 XIIa 的比例为 90.0%（216/240）；种的亚基因型 IIdA20G1 和 IIaA15G2R1 的比例分别为 15.4%（62/402）和 19.7%（79/402）。结果表明，在欧洲种是优势种，而在大洋洲、亚洲和非洲种是优势种，在北美洲和南美洲种是优势种。种的亚基因型 IIa 在全球绵羊中广泛分布。结果强调了绵羊作为人畜共患隐孢子虫储存宿主的作用，需要进一步研究该病原体在绵羊中的流行情况、传播和控制。
