Akatay Emre Alp, Bayraktar Deniz, Otman Eda, Ustun Oguz, Kurut Aysin Idil, Sarac Devrim Can, Atalay Busranur, Ramazanoglu Irem, Tekin Ilyas, Kurum Tugba, Gucenmez Sercan, Ozmen Mustafa, Akar Servet
Department of Physiotherapy and Rehabilitation, Institute of Health Sciences, Izmir Katip Celebi University, Izmir, Turkey.
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Izmir Katip Celebi University, Izmir, Turkey.
Z Rheumatol. 2024 Feb;83(Suppl 1):183-190. doi: 10.1007/s00393-022-01267-5. Epub 2022 Sep 8.
Systemic sclerosis (SSc) is a connective tissue disorder characterized by collagen deposits in various organs. Skin involvement is one of the most common symptoms and along with vascular damage, may deteriorate hand functions. However, the status of hand functions has generally been investigated using patient-reported measures in patients with SSc. The aim of the present study was to investigate performance-based hand functions in patients with SSc using the Sollerman Hand Function Test (SHFT).
A total of 39 patients with SSc (33 females) were included in the study. Twenty-four patients were classified as limited cutaneous SSc (lcSSc), while 15 patients were classified as diffuse cutaneous SSc (dcSSc). Hand-related physical characteristics were evaluated using the Modified Hand Mobility in Scleroderma Test, grip strength, and pinch strengths. The Duruoz Hand Index (Cochin Hand Functional Disability Scale), Disability of Arm, Shoulder, and Hand Questionnaire, Health Assessment Questionnaire, and Scleroderma Health Assessment Questionnaire were used as patient-reported measures. Performance-based hand functions were evaluated using SHFT.
No significant differences were observed between lcSSc and dcSSc subtypes regarding performance-based and patient-reported hand functions (p > 0.05). SHFT scores significantly correlated with hand-related physical characteristics and patient-reported hand functions (p < 0.05). The highest correlation was determined between SHFT and the Duruoz Hand Index (rho: -0.652, p < 0.001).
According to our results, performance-based hand functions seem not to be affected by disease subtype. Performance-based hand functions may partially be captured by the patient-reported outcomes, especially the Duruoz Hand Index, in patients with SSc.
系统性硬化症（SSc）是一种结缔组织疾病，其特征是在各个器官中存在胶原蛋白沉积。皮肤受累是最常见的症状之一，并且与血管损伤一起，可能会使手部功能恶化。然而，SSc患者的手部功能状况通常是通过患者报告的测量方法进行研究的。本研究的目的是使用索勒曼手部功能测试（SHFT）来研究SSc患者基于表现的手部功能。
本研究共纳入39例SSc患者（33例女性）。24例患者被分类为局限性皮肤型SSc（lcSSc），而15例患者被分类为弥漫性皮肤型SSc（dcSSc）。使用改良的硬皮病手部活动度测试、握力和捏力来评估与手部相关的身体特征。使用迪鲁兹手部指数（科钦手部功能残疾量表）、手臂、肩部和手部功能障碍问卷、健康评估问卷和硬皮病健康评估问卷作为患者报告的测量方法。使用SHFT评估基于表现的手部功能。
在基于表现的和患者报告的手部功能方面，lcSSc和dcSSc亚型之间未观察到显著差异（p>0.05）。SHFT评分与与手部相关的身体特征和患者报告的手部功能显著相关（p<0.05）。SHFT与迪鲁兹手部指数之间的相关性最高（rho：-0.652，p<0.001）。
根据我们的结果表明，基于表现的手部功能似乎不受疾病亚型的影响。在SSc患者中，基于表现的手部功能可能部分地被患者报告的结果所反映，特别是迪鲁兹手部指数。
