Department of Obstetrics and Gynecology, Arash Women's Hospital, University of Medical Sciences, Tehran, Iran.
Department of Obstetrics and Gynecology, Arash Women's Hospital, University of Medical Sciences, Tehran, Iran.
Vaccine. 2023 Feb 17;41(8):1490-1495. doi: 10.1016/j.vaccine.2023.01.022. Epub 2023 Jan 16.
Evaluation of covid‑19 vaccine hesitancy among pregnant women and their reported reasons for vaccine refusal.
This prospective study was performed in Arash women's Hospital, Tehran, Iran, between December 1, 2021 and January 1, 2022. All pregnant women who were attended to prenatal care unit were considered eligible for inclusion. A validated questionnaire was used for data gathering. Written informed consent was obtained from all participants.
Finally, 477 pregnant women were recruited and were divided into two groups according the status of vaccine acceptance (237 accepted and 240 women refused vaccination). The mean age of accepted participants was higher (31.65 ± 5.69 vs 30.39 ± 5.5; P = 0.01). There was a significant statistical difference between the groups regarding education level. Access to internet and social media were also significantly different between the two groups (94.8% in accepted vs 86.6% in refused group; P = 0.002). There was more rate of severe COVID-19 infection in friends or relatives of accepted group (50% vs 38%). we did not find any statistically significant differences in obstetric characteristics and the rate of obstetric complications between the two groups. The most common reasons reported by participants for vaccine refusal, was fear of vaccination side effects on the fetus (86.5%), and the less common reported reasons were husband's disagreement (9.7%), use of traditional medicine (5.6%), religious beliefs (3.7%), and information obtained from social media (2.8%). After advices from medical staff, most of these mothers (86.5%) still refused vaccination.
Based on the results of the present study,rate of COVID-19 vaccine hesitancy was about 50% and its most common reported reason was fear of probable side effects of vaccine on the fetus.
评估孕妇对 COVID-19 疫苗的犹豫态度及其拒绝接种疫苗的原因。
本前瞻性研究于 2021 年 12 月 1 日至 2022 年 1 月 1 日在伊朗德黑兰的 Arash 妇女医院进行。所有接受产前保健的孕妇均符合纳入标准。使用经过验证的问卷收集数据。所有参与者均获得书面知情同意。
最终，共招募了 477 名孕妇，并根据疫苗接种接受情况将其分为两组（237 名接受组和 240 名拒绝接种组）。接受组参与者的平均年龄较高（31.65±5.69 岁比 30.39±5.5 岁；P=0.01）。两组在教育水平方面存在显著的统计学差异。两组在互联网和社交媒体的使用方面也存在显著差异（接受组 94.8%，拒绝组 86.6%；P=0.002）。接受组中朋友或亲戚中有更多严重 COVID-19 感染病例（50%比 38%）。两组在产科特征和产科并发症发生率方面无统计学差异。参与者报告的拒绝接种疫苗的最常见原因是担心疫苗对胎儿的副作用（86.5%），其次是丈夫不同意（9.7%）、使用传统医学（5.6%）、宗教信仰（3.7%）和从社交媒体获取的信息（2.8%）。在医务人员的建议下，这些母亲中的大多数（86.5%）仍拒绝接种疫苗。
根据本研究结果，COVID-19 疫苗犹豫率约为 50%，其最常见的报告原因是担心疫苗对胎儿可能产生的副作用。
