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纳米生物技术:大脑疾病的新前沿。

Nanobiotechnology: A New Frontier for Brain Disorders.

机构信息

Istituto per la Ricerca e l'Innovazione Biomedica, CNR, Via U. La Malfa 153, 90146 Palermo, Italy.

Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy.

出版信息

Int J Mol Sci. 2022 Aug 24;23(17):9603. doi: 10.3390/ijms23179603.

DOI:10.3390/ijms23179603
PMID:36076998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9455621/
Abstract

Brain disorders, such as neurodegenerative diseases (NDs) and tumors (more than 600 pathologies), are a serious health problem, resulting in brain dysfunctions that limit normal activities, with a significant economic impact [...].

摘要

脑部疾病,如神经退行性疾病(NDs)和肿瘤(超过 600 种病变),是一个严重的健康问题,导致大脑功能障碍,限制了正常活动,产生重大的经济影响[...]。

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Nanobiotechnology: A New Frontier for Brain Disorders.纳米生物技术:大脑疾病的新前沿。
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2
Promising Treatment for Multiple Sclerosis: Mitochondrial Transplantation.有望治疗多发性硬化症的新方法:线粒体移植。
Int J Mol Sci. 2022 Feb 17;23(4):2245. doi: 10.3390/ijms23042245.
3
The Mechanisms Underlying the Protective Action of Selenium Nanoparticles against Ischemia/Reoxygenation Are Mediated by the Activation of the Ca Signaling System of Astrocytes and Reactive Astrogliosis.硒纳米粒子对缺血/再灌注损伤的保护作用机制是通过激活星形胶质细胞的钙信号系统和反应性星形胶质增生介导的。
Int J Mol Sci. 2021 Nov 26;22(23):12825. doi: 10.3390/ijms222312825.
4
Nano-structured myelin: new nanovesicles for targeted delivery to white matter and microglia, from brain-to-brain.纳米结构髓磷脂:用于从脑到脑靶向递送至白质和小胶质细胞的新型纳米囊泡。
Mater Today Bio. 2021 Oct 7;12:100146. doi: 10.1016/j.mtbio.2021.100146. eCollection 2021 Sep.
5
Extracellular Vesicles from Human Teeth Stem Cells Trigger ATP Release and Promote Migration of Human Microglia through P2X4 Receptor/MFG-E8-Dependent Mechanisms.人牙髓干细胞来源的细胞外囊泡通过 P2X4 受体/MFG-E8 依赖的机制触发 ATP 释放并促进人小胶质细胞迁移。
Int J Mol Sci. 2021 Oct 11;22(20):10970. doi: 10.3390/ijms222010970.
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Exosomes in Alzheimer's Disease: From Being Pathological Players to Potential Diagnostics and Therapeutics.阿尔茨海默病中的细胞外囊泡:从病理参与者到潜在的诊断和治疗方法。
Int J Mol Sci. 2021 Oct 6;22(19):10794. doi: 10.3390/ijms221910794.
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Tomato Bushy Stunt Virus Nanoparticles as a Platform for Drug Delivery to Shh-Dependent Medulloblastoma.番茄丛矮病毒纳米颗粒作为一种平台,用于向 Shh 依赖性髓母细胞瘤递药。
Int J Mol Sci. 2021 Sep 29;22(19):10523. doi: 10.3390/ijms221910523.
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