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Depletion of γδ T Cells Leads to Reduced Angiogenesis and Increased Infiltration of Inflammatory M1-like Macrophages in Ischemic Muscle Tissue.γδ T 细胞耗竭导致缺血性肌肉组织中血管生成减少和炎症 M1 样巨噬细胞浸润增加。
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Proteostasis Perturbations and Their Roles in Causing Sterile Inflammation and Autoinflammatory Diseases.蛋白质稳态紊乱及其在引起无菌性炎症和自身炎症性疾病中的作用。
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Albumin Might Attenuate Bacteria-Induced Damage on Kupffer Cells for Patients with Chronic Liver Disease.白蛋白可能减轻慢性肝病患者库普弗细胞的细菌诱导损伤。
Cells. 2021 Sep 3;10(9):2298. doi: 10.3390/cells10092298.
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Crosstalk between Interleukin-1β and Type I Interferons Signaling in Autoinflammatory Diseases.白细胞介素-1β与Ⅰ型干扰素信号在自身炎症性疾病中的相互作用。
Cells. 2021 May 8;10(5):1134. doi: 10.3390/cells10051134.

先天免疫的最新研究进展概述。

State of the Art of Innate Immunity-An Overview.

机构信息

Institute of Biochemistry, Justus-Liebig-University, 35392 Giessen, Germany.

Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University, 81377 Munich, Germany.

出版信息

Cells. 2022 Aug 30;11(17):2705. doi: 10.3390/cells11172705.

DOI:10.3390/cells11172705
PMID:36078113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9454720/
Abstract

The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) as well as danger-associated molecular patterns (DAMPs) by pathogen-recognition receptors (PRRs), and produces proinflammatory and antiviral cytokines and chemokines [...].

摘要

固有免疫系统通过病原体识别受体（PRRs）识别病原体相关分子模式（PAMPs）和危险相关分子模式（DAMPs），是抵御细菌和病毒感染以及无菌性炎症的第一道防线，并产生促炎和抗病毒细胞因子和趋化因子[...]。