先天免疫的最新研究进展概述。
State of the Art of Innate Immunity-An Overview.
机构信息
Institute of Biochemistry, Justus-Liebig-University, 35392 Giessen, Germany.
Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University, 81377 Munich, Germany.
出版信息
Cells. 2022 Aug 30;11(17):2705. doi: 10.3390/cells11172705.
Abstract
The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) as well as danger-associated molecular patterns (DAMPs) by pathogen-recognition receptors (PRRs), and produces proinflammatory and antiviral cytokines and chemokines [...].
摘要
固有免疫系统通过病原体识别受体（PRRs）识别病原体相关分子模式（PAMPs）和危险相关分子模式（DAMPs），是抵御细菌和病毒感染以及无菌性炎症的第一道防线，并产生促炎和抗病毒细胞因子和趋化因子[...]。
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