Department of Family Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City 740500, Vietnam.
Nguyen Tri Phuong Hospital, Ho Chi Minh City 740500, Vietnam.
Int J Environ Res Public Health. 2022 Sep 4;19(17):11088. doi: 10.3390/ijerph191711088.
to determine modifiable risk factors of exacerbations in chronic respiratory diseases with airways obstruction (i.e., asthma and COPD) in southern Vietnam.
an environmental and health-related behavioural questionnaire was submitted to patients with both chronic respiratory symptoms and airways obstruction. An exacerbation was defined as any acute worsening in clinical symptoms requiring a change in treatment, in a patient receiving prophylactic therapy.
235 patients were evaluated, including 131 (56%) chronic obstructive pulmonary disease (COPD) and 104 (44%) asthmatics. There were 75% males and 69% smokers. Occupational exposure accounted for 66%, mainly among construction and industry workers. Smoking was associated with more severe airways obstruction. Respiratory exacerbations were reported in 56/235 patients (24%). The risk of exacerbation was increased in patients with a lower education level, exposure to occupational pollutants, cumulative smoking ≥ 20 pack year, housing space < 10 m, and poorly ventilated housing. Based on multivariate analysis, the risk of exacerbation remained significantly higher among patients with occupational exposure and low housing space per person.
besides smoking cessation, more supportive policies, including improvement of occupational environment and housing design for better ventilation, are needed to prevent the severity of chronic respiratory diseases in Vietnam.
在越南南部确定可改变气道阻塞性慢性呼吸系统疾病（即哮喘和 COPD）恶化的风险因素。
向有慢性呼吸系统症状和气道阻塞的患者提交了一份环境和与健康相关的行为问卷。加重定义为正在接受预防治疗的患者的临床症状任何急性恶化，需要改变治疗。
共评估了 235 名患者，包括 131 名（56%）慢性阻塞性肺疾病（COPD）和 104 名（44%）哮喘患者。男性占 75%，吸烟者占 69%。职业暴露占 66%，主要发生在建筑和工业工人中。吸烟与更严重的气道阻塞有关。235 名患者中有 56 名（24%）报告有呼吸道恶化。教育程度较低、接触职业污染物、累积吸烟≥20 包年、住房面积<10 平方米和通风不良的住房与加重风险增加有关。基于多变量分析，职业暴露和人均住房空间较小的患者发生恶化的风险仍然明显更高。
除了戒烟外，还需要更多的支持性政策，包括改善职业环境和住房设计以改善通风，以防止越南慢性呼吸系统疾病的严重程度。
