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验证接受化疗的肿瘤患者的食物摄入视觉/言语模拟量表(Ingesta-VVAS)。

Validation of the Visual/Verbal Analogue Scale of Food Ingesta (Ingesta-VVAS) in Oncology Patients Undergoing Chemotherapy.

机构信息

Department of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.

Department of Internal Medicine, Flevoziekenhuis, 1315 RA Almere, The Netherlands.

出版信息

Nutrients. 2022 Aug 26;14(17):3515. doi: 10.3390/nu14173515.

Abstract

This study aimed to: (1) externally validate the Visual/Verbal Analogue Scale of food ingesta (ingesta-VVAS) that previously showed good discrimination between oncology patients who ingest more or less energy than required; (2) explore the discriminative properties of other questions. Dietitians performed 322 interviews in 206 adult oncology patients undergoing chemotherapy in two Dutch hospitals, including a 24-h dietary recall, assessment of the ingesta-VVAS and 12 additional questions related to reduced food intake. The ingesta-VVAS score was linearly associated with energy intake as % of Total Energy Expenditure (TEE) (standardized beta = 0.39, p < 0.001), with no differences between groups based on use of oral nutritional supplements, body mass index, in/outpatient setting or sex. The accuracy of the ingesta-VVAS score to predict low energy intake (<75% of TEE) was poor (Area Under the Receiver Operating Characteristic curve (AUC) = 0.668, 95% CI 0.603−0.733). The optimal multivariate model included the ingesta-VVAS score and a question on ‘feeling sick’ (AUC = 0.680, 95% CI 0.615−0.746). In conclusion, in our study the ingesta-VVAS discriminates poorly between oncology patients undergoing chemotherapy who ingest more or less energy than required. Adding a question on feeling sick only slightly improved model performance. Further external validation is warranted.

摘要

本研究旨在

(1) 对先前显示出能够区分摄入能量多于或少于所需的肿瘤患者的视觉/语言模拟量表(ingesta-VVAS)进行外部验证;(2) 探索其他问题的区分性能。营养师对两家荷兰医院接受化疗的 206 名成年肿瘤患者进行了 322 次访谈,其中包括 24 小时膳食回顾、ingesta-VVAS 评估和 12 个与减少食物摄入相关的附加问题。ingesta-VVAS 评分与作为总能量消耗 (TEE) 的能量摄入百分比呈线性相关(标准化β=0.39,p<0.001),在是否使用口服营养补充剂、体重指数、住院/门诊环境或性别方面,两组之间没有差异。ingesta-VVAS 评分预测低能量摄入(<TEE 的 75%)的准确性较差(受试者工作特征曲线下面积 (AUC) = 0.668,95%CI 0.603−0.733)。最优的多变量模型包括 ingesta-VVAS 评分和一个关于“感觉不适”的问题(AUC = 0.680,95%CI 0.615−0.746)。总之,在我们的研究中,ingesta-VVAS 对接受化疗的摄入能量多于或少于所需的肿瘤患者的区分能力较差。添加一个关于感觉不适的问题仅略微提高了模型性能。需要进一步的外部验证。

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