O'Dell Leslie, Dierker Damon S, Devries Douglas K, Garlich Jaclyn, Whitley Walter O, Holdbrook Mark, Baba Stephanie N, Yeu Elizabeth
Medical Optometry America, Shrewsbury, PA, USA.
Eye Surgeons of Indiana, Indianapolis, IN, USA.
Clin Ophthalmol. 2022 Sep 2;16:2979-2987. doi: 10.2147/OPTH.S374530. eCollection 2022.
To evaluate the impact of blepharitis on patients' daily activities and quality of life.
In this multicenter, observational, prospective, IRB-approved study, 311 blepharitis patients aged ≥18 years were included. blepharitis was diagnosed based on the presence of ≥1.0 mite per lash (upper and lower eyelids combined), >10 collarettes on the upper lashes, and at least mild lid margin erythema of the upper eyelid in at least one eye. All patients were asked to complete a questionnaire about their symptoms, daily activities, quality of life, and management approaches, and descriptive statistics were used to analyze the responses.
More than half the patients had been experiencing symptoms of blepharitis for ≥4 years. The three most frequent and bothersome symptoms experienced by patients were dry eyes, itchiness, and irritation. Nearly half the patients (47%) responded that they were conscious of their eyes all day, and 23% said that they were constantly worrying about their eyes. Other activities that were negatively affected included difficulty driving at night (47%), additional time needed for daily hygiene routine (30%), and difficulty in wearing eye make-up (in 34% of females). While all subjects had objective signs of blepharitis confirmed by an eye care provider, 58% said they had never previously been diagnosed with blepharitis. The most commonly used management approaches for blepharitis were artificial tears (47%), warm compresses (32%), and lid wipes (14%).
blepharitis has a significant negative impact on daily activities and the mental and physical well-being of afflicted patients.
评估睑缘炎对患者日常活动及生活质量的影响。
在这项经机构审查委员会批准的多中心、观察性、前瞻性研究中，纳入了311名年龄≥18岁的睑缘炎患者。睑缘炎的诊断依据为每根睫毛（上下眼睑合计）螨虫数量≥1.0只、上睑睫毛上有>10个睫毛胶套，且至少一只眼睛的上眼睑存在至少轻度的睑缘红斑。所有患者均被要求完成一份关于其症状、日常活动、生活质量及治疗方法的问卷，并采用描述性统计分析这些回答。
超过半数患者出现睑缘炎症状已≥4年。患者经历的最常见且最困扰的三种症状为干眼、瘙痒和刺激感。近半数患者（47%）表示一整天都在留意自己的眼睛，23%的患者称他们一直在担心自己的眼睛。其他受到负面影响的活动包括夜间驾驶困难（47%）、日常卫生清洁需要额外时间（30%）以及女性化妆困难（34%）。虽然所有受试者均有眼科护理人员确认的睑缘炎客观体征，但58%的患者表示他们之前从未被诊断出患有睑缘炎。治疗睑缘炎最常用的方法是人工泪液（47%）、热敷（32%）和眼睑擦拭（14%）。
睑缘炎对患者的日常活动以及身心健康有显著负面影响。
