Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
J Agric Food Chem. 2022 Sep 21;70(37):11500-11509. doi: 10.1021/acs.jafc.2c05309. Epub 2022 Sep 9.
Oils are among the most important agricultural commodities and have wide applications in food/nutrition, biofuels, and oleochemicals. The oleaginous microalga can produce large amounts of oils and the high-value ω-3 eicosapentaenoic acid, which represents a promising resource for oil production targeting biodiesel, nutraceutical, and aquaculture industries. In recent years, with the availability of omics databases and the development of genetic tools, has been extensively investigated as a model photosynthetic organism for studying lipid metabolism and as a green cellular factory to produce lipids for industrial applications. This review summarizes the current knowledge on the lipid composition and biosynthetic pathways of and reviews the recent advances in metabolic engineering of lipid production in this microalga.
油是最重要的农产品之一，在食品/营养、生物燃料和油脂化学品方面有广泛的应用。产油微藻可以大量生产油脂和高附加值的ω-3 二十碳五烯酸，这是一种有前途的生物柴油、营养保健品和水产养殖产业的油脂生产资源。近年来，随着组学数据库的出现和遗传工具的发展，已被广泛研究作为一种模式光合生物，用于研究脂质代谢，并作为一种绿色细胞工厂，生产用于工业应用的脂质。本综述总结了关于 的脂质组成和生物合成途径的现有知识，并回顾了在这种微藻中进行脂质生产的代谢工程的最新进展。
