Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:846-849. doi: 10.1109/EMBC48229.2022.9871073.
Microneedle-based electrodes have attracted significant attention for the monitoring of physiological signals, including ECG, EMG, and E OG, as they have the potential to eliminate the skin preparation and stability issues associated with conventional wet gel electrodes. This paper describes the development of a polymeric flexible microneedle electrode (FMNE) that does not require skin abrasion and can be used for long-term ECG monitoring. Fabricated using a combination of epoxy resin microneedles bonded to a flexible substrate, the performance of the FMNE was compared to that of a conventional wet-gel electrode by simultaneously capturing the ECG signal using both electrodes, and estimating the signal-to-noise ratio (SNR) of each. Results show that the flexible electrode can acquire ECG signals in which all the characteristic components of the wave are visible, and that are comparable in quality to those obtained using commercial wet electrodes. Bland-Altman plots were drawn to validate the performance of FMNE, and show that the mean difference ± standard deviation in SNR obtained using wet electrodes and FMNE was [Formula: see text]. Clinical Relevance- These microneedle-based 'dry electrodes' could be used in long-term monitoring of biopotential activity.
基于微针的电极在监测生理信号方面引起了广泛关注，包括心电图（ECG）、肌电图（EMG）和脑电图（EEG），因为它们有可能消除与传统湿凝胶电极相关的皮肤准备和稳定性问题。本文描述了一种聚合物柔性微针电极（FMNE）的开发，该电极不需要皮肤磨损，可用于长期 ECG 监测。该电极由环氧树脂微针与柔性基底结合制成，通过同时使用两种电极捕获 ECG 信号，并估计每个电极的信噪比（SNR），比较了 FMNE 的性能。结果表明，柔性电极可以获取所有特征波成分可见的 ECG 信号，其质量与使用商业湿电极获得的信号相当。绘制 Bland-Altman 图以验证 FMNE 的性能，结果表明使用湿电极和 FMNE 获得的 SNR 的平均差异±标准偏差为[公式：见文本]。临床相关性-这些基于微针的“干电极”可用于生物电位活动的长期监测。
