Clark C V, Mapstone R
Doc Ophthalmol. 1986;64(2):179-85. doi: 10.1007/BF00159992.
Systemic autonomic nerve function was assessed in 67 patients with open-angle glaucoma and 76 age- and sex-matched control subjects, using a series of well-established tests based upon cardiovascular reflex responses to standardised stimuli. Parasympathetic neuropathy was present in 37.3% of open-angle glaucoma patients compared with 2.6% of the control group. Demonstration of a significant association between autonomic neuropathy and primary glaucoma may provide a logical rationale for the efficacy of autonomic medication in glaucoma therapeutics; the prognostic implications are discussed.
对67例开角型青光眼患者和76例年龄及性别匹配的对照者进行了全身自主神经功能评估，采用了一系列基于对标准化刺激的心血管反射反应的成熟测试。开角型青光眼患者中37.3%存在副交感神经病变，而对照组这一比例为2.6%。自主神经病变与原发性青光眼之间存在显著关联，这可能为自主神经药物在青光眼治疗中的疗效提供合理依据；文中讨论了其预后意义。
