Lee Boram, Kwon Chan-Young, Park Man Young
KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Department of Oriental Neuropsychiatry, Dong-Eui University College of Korean Medicine, Busan 47227, Republic of Korea.
Evid Based Complement Alternat Med. 2022 Aug 31;2022:6429836. doi: 10.1155/2022/6429836. eCollection 2022.
Chronic rhinosinusitis (CRS) is a highly prevalent disease associated with poor quality of life. In this paper, we appraised the role of acupuncture in the treatment of CRS.
Electronic databases were searched for randomized controlled clinical trials (RCTs) that examined the role of acupuncture in CRS. The primary outcome measures included posttreatment CRS severity, as measured by the Visual Analogue Scale (VAS) and Total Effective Rate (TER). The risk of bias and quality of evidence were evaluated according to the Cochrane Collaboration's risk-of-bias tool and GRADE tool, respectively.
Evidence from the RCTs ( = 10) suggested that acupuncture as a monotherapy or adjunctive therapy to conventional treatment was associated with significant improvements in VAS, TER, and quality of life when compared with conventional treatments for CRS. However, there was a similar incidence of adverse events. The risk of bias was unclear and the quality of evidence for each finding was generally moderate to low.
Acupuncture as a stand-alone or adjunctive treatment for CRS was associated with clinical symptom improvement and better quality of life, without any risk for serious adverse events. However, the high clinical heterogeneity of the included RCTs and overall moderate-to-low quality of evidence necessitates rigorous, well-designed trials to confirm these findings. . This trial is registered with PROSPERO (no. CRD42021292135).
慢性鼻-鼻窦炎（CRS）是一种高发性疾病，会导致生活质量下降。在本文中，我们评估了针灸在CRS治疗中的作用。
检索电子数据库，查找检验针灸在CRS中作用的随机对照临床试验（RCT）。主要结局指标包括治疗后CRS严重程度，通过视觉模拟量表（VAS）和总有效率（TER）进行测量。分别根据Cochrane协作网的偏倚风险工具和GRADE工具评估偏倚风险和证据质量。
来自10项RCT的证据表明，与CRS的传统治疗方法相比，针灸作为单一疗法或传统治疗的辅助疗法，在VAS、TER和生活质量方面有显著改善。然而，不良事件的发生率相似。偏倚风险尚不清楚，每项研究结果的证据质量一般为中等至低等。
针灸作为CRS的单独治疗或辅助治疗与临床症状改善及更好的生活质量相关，且无严重不良事件风险。然而，纳入的RCT临床异质性高，总体证据质量中等至低等，因此需要进行严格、设计良好的试验来证实这些发现。本试验已在国际前瞻性注册平台（PROSPERO）注册（注册号：CRD42021292135）。
