Kudriashov B A, Ammosova Ia M, Liapina L A, Ul'ianov A M
Farmakol Toksikol. 1987 May-Jun;50(3):49-52.
The diabetogenic factor (DGF) isolated from the human blood and the blood of rats with diabetes mellitus was shown to be a protein homogeneous at electrophoresis in gel of polyacrylamide, with the molecular weight of 60,000 D. The interaction of DGF with heparin results in the formation of a complex in which the factor's properties are blocked and those of heparin as a anticoagulant are preserved.
从人类血液和糖尿病大鼠血液中分离出的致糖尿病因子(DGF)在聚丙烯酰胺凝胶电泳中显示为一种分子量为60,000道尔顿的蛋白质,具有均一性。DGF与肝素相互作用会形成一种复合物,其中该因子的特性被阻断,而肝素作为抗凝剂的特性得以保留。