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2019 年,刚果民主共和国农村地区 Gombe-Matadi 成年人中,由于未进行口服葡萄糖耐量试验,糖尿病患病率和相关风险因素被低估。

Diabetes prevalence and risk factors, underestimated without oral glucose tolerance test, in rural Gombe-Matadi Adults, Democratic Republic of Congo, 2019.

机构信息

Department of Nutrition, School of Public Health, Epidemiology Center of Diabetes, Kinshasa, Democratic Republic of Congo.

Education Center of Diabetes and Health, Epidemiology Center of Diabetes, Kinshasa, Democratic Republic of Congo.

出版信息

Sci Rep. 2022 Sep 12;12(1):15293. doi: 10.1038/s41598-022-18658-y.

DOI:10.1038/s41598-022-18658-y
PMID:36097182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9467973/
Abstract

An increase in the diabetes prevalence is reported worldwide. We aimed to determine the diabetes prevalence and its risk factors among adults in a rural area of the Democratic Republic of Congo. A cross-sectional study was conducted in 1531 inhabitants, selected by five stages, in the Health Zone of Gombe-Matadi. Diabetes was defined according to the American Diabetes Association and the International Diabetes Federation. Fasting glycemia and/or an oral glucose tolerance test were collected. We measured body mass index, waist circumference and blood pressure. Mann Whitney's and chi-square tests compared respondents with non-respondents. Multivariable logistic regression measured associations between diabetes and its risk factors. Crude and standardized prevalence of diabetes were 6.7% and 5.3%, respectively. Undiagnosed diabetes accounted for 58.8%. The oral glucose tolerance test alone diagnosed 2.6% of cases. Diabetes was more frequent in males, unemployed, obese and hypertensive (p < 0.05). Risk factors for diabetes were being male, aged ≥ 40 years, general and abdominal obesity associated with elderly, family history of diabetes, and hypertension. Diabetes in rural areas of the Democratic Republic of Congo appears to be underdiagnosed. The oral glucose tolerance test provides an opportunity to screen individuals for diabetes in this setting.

摘要

全球范围内糖尿病患病率呈上升趋势。我们旨在确定刚果民主共和国农村地区成年人的糖尿病患病率及其危险因素。在戈马-马塔迪卫生区,通过五个阶段选择了 1531 名居民进行了横断面研究。糖尿病的定义符合美国糖尿病协会和国际糖尿病联合会的标准。采集了空腹血糖和/或口服葡萄糖耐量试验。我们测量了体重指数、腰围和血压。曼-惠特尼检验和卡方检验比较了应答者和未应答者。多变量逻辑回归测量了糖尿病及其危险因素之间的关联。糖尿病的粗患病率和标准化患病率分别为 6.7%和 5.3%。未确诊的糖尿病占 58.8%。单独口服葡萄糖耐量试验诊断出 2.6%的病例。男性、失业、肥胖和高血压患者的糖尿病更为常见(p < 0.05)。糖尿病的危险因素包括男性、年龄≥40 岁、与老年人相关的全身和腹部肥胖、糖尿病家族史和高血压。刚果民主共和国农村地区的糖尿病似乎诊断不足。口服葡萄糖耐量试验为该环境下筛查糖尿病患者提供了机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb2/9467973/d16ddea2243b/41598_2022_18658_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb2/9467973/187ad24c4185/41598_2022_18658_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb2/9467973/d16ddea2243b/41598_2022_18658_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb2/9467973/187ad24c4185/41598_2022_18658_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb2/9467973/d16ddea2243b/41598_2022_18658_Fig2_HTML.jpg

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