Al-Hajjaj Maher, Alam Oula Abou, Alqralleh Muna, Zakkor Mohammed Deeb, Almarawi Hussin
Department of Urology, Aleppo University Hospital, Aleppo, Syria.
Jordan University of Science & Technology, Irbid, Jordan.
Ann Med Surg (Lond). 2022 Oct;82:104605. doi: 10.1016/j.amsu.2022.104605. Epub 2022 Sep 8.
COVID-19 disease is considered a highly risky pandemic which led to more victims during the last two years.
We present a case of a 32 athlete male patient who presented with covid-19 symptoms. Past medical history was unremarkable except for oxandrolone (an anabolic steroid) 30/day for bodybuilding 21 days before the presentation. He reported that his symptoms developed rapidly in the past two days. After taking patient consent, we started the treatment with a single dose of anti-androgen (proxlatumide 400 mg) followed by 200 mg daily for one week. There was no need for hospital admission. On-call follow-up showed a marked response with resolving of most symptoms. Follow-up for six weeks later demonstrated a full recovery.
Using anabolic androgen steroids have been considered a risk factor for developing pneumonia. With the wide use between bodybuilders, many reports showed a link between the use of such drugs and COVID-19 disease. Anti-androgen drugs may lead to resolution of the symptoms.
To the best of our knowledge, this is the second case reporting the link between anabolic steroids use and covid-19 disease severity.
新冠肺炎被认为是一种高风险的大流行病，在过去两年导致了更多的受害者。
我们报告一例32岁男性运动员患者，出现了新冠肺炎症状。既往病史无异常，仅在就诊前21天为健身每日服用30毫克氧雄龙（一种合成代谢类固醇）。他报告称，其症状在过去两天迅速发展。在获得患者同意后，我们开始用单剂量抗雄激素药物（400毫克普拉克胺）治疗，随后每日200毫克，持续一周。无需住院治疗。随诊显示症状有明显改善，多数症状消退。六周后的随访显示完全康复。
使用合成代谢雄激素类固醇被认为是发生肺炎的一个风险因素。随着其在健美运动员中的广泛使用，许多报告显示此类药物的使用与新冠肺炎之间存在关联。抗雄激素药物可能会使症状消退。
据我们所知，这是第二例报告合成代谢类固醇使用与新冠肺炎疾病严重程度之间关联的病例。
